(data stored in SCRATCH zone)

SWISSPROT: B2UHK4_RALPJ

ID   B2UHK4_RALPJ            Unreviewed;      1183 AA.
AC   B2UHK4;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 76.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACD29055.1};
GN   OrderedLocusNames=Rpic_3950 {ECO:0000313|EMBL:ACD29055.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29055.1, ECO:0000313|Proteomes:UP000002566};
RN   [1] {ECO:0000313|Proteomes:UP000002566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J {ECO:0000313|Proteomes:UP000002566};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001069; ACD29055.1; -; Genomic_DNA.
DR   RefSeq; WP_012430081.1; NC_010678.1.
DR   STRING; 402626.Rpic_3950; -.
DR   EnsemblBacteria; ACD29055; ACD29055; Rpic_3950.
DR   GeneID; 6285176; -.
DR   KEGG; rpi:Rpic_3950; -.
DR   PATRIC; fig|402626.5.peg.189; -.
DR   eggNOG; ENOG4105BZU; Bacteria.
DR   eggNOG; COG2200; LUCA.
DR   eggNOG; COG2770; LUCA.
DR   HOGENOM; HOG000001159; -.
DR   OMA; IVYTHMT; -.
DR   OrthoDB; 1635706at2; -.
DR   BioCyc; RPIC402626:GH94-3951-MONOMER; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00130; PAS; 3.
DR   Gene3D; 3.20.20.450; -; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF08447; PAS_3; 2.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; SSF141868; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   SUPFAM; SSF55785; SSF55785; 3.
DR   TIGRFAMs; TIGR00254; GGDEF; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50113; PAC; 3.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
DR   PRODOM; B2UHK4.
DR   SWISS-2DPAGE; B2UHK4.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002566};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002566};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     15     37       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    281    304       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      306    360       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      451    503       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      578    630       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      627    684       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN      699    755       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      787    915       GGDEF. {ECO:0000259|PROSITE:PS50887}.
FT   DOMAIN      924   1179       EAL. {ECO:0000259|PROSITE:PS50883}.
FT   COILED      494    514       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1183 AA;  130440 MW;  0BF9D49A14CA8D91 CRC64;
     MPKHAFFPTT LRGRLLALAA VAALPAIVVA IAGVALYRDR LNDHLAQHLT HETETAAARV
     GMVLSNANTL LSVLIADDSA LRMERQECSS FVNRVFHNQS ELANLGIIDA HRKLVCTPDT
     AKLAIDLSDR PYINEIMATG RPSLSTFVIG RVSGQAVLIS ARPMAGNDGT IRGVAYAAVR
     QSALIAAAVD GMSEAPVYLV DAAGNVLSTH GALEAAQVPA IVRGPLVAAA AQQPGEPVFV
     DDTDGVRRAY AAMVVPHAAG GHLRIVRGVD ATDIVRQQRN VTLAGGGAIL LMVVMLLALI
     QMALRRMVMP RIDALVDAAR HYATGDFSAR VPEHGSSRDE LSLLERTFNE MRAAIQRHDA
     TVHRLTERFQ RVARATNDWI FDWDIATGES WANASLHRLL GSDALLGQGD DDGTGGGTSR
     TLTFQQFVHP DDVDAFAHEL RTVLNSDRDS WQHVCRVIDA NRATRTVEIR ASLYRDQDGR
     AVRMVGGVTD ISQRSAIEQE LRSSEANLRV AEQIALLGSW RWDVLRDSTT WSSGMYVLTG
     MPPGAPPAFA QQAQFFTADS YNRLREAASR AVTEGEAYSL ELEMIRRDGE HRWVLSRGNI
     ERNDRDEVVA LFGTMQDITD RRESDEQLRL LRRVVESVPS GITVADAQQP DFPIVYVNPG
     FERMTGYRAE EILGRNARFL HSSEPGQPAL NEVRTALRDE SEIRVLLRNF RKDGHAFLNN
     FLLSPVRDAK GAVTHYVGIQ DDVTEQEMTR TRLAQHATID SLTGLPNRTL LADRVQQSVE
     MAARQRSRFY VALVNIDRFK VVNDSLGHLL GDEVLRRVAE RLRDAADTVD TVARFGGDVF
     ALVISHAGSR GVDFGFDLFA EPVRVEGHEV FVTASIGVAE YPAHGADADS LIRHAEMAMY
     YAKQNGRNRL EFFAPEMDIG VSYRLNLEHQ IRATLEQGQF RLLYQPQIDT KTGRVCGLEA
     LIRWIHPTRG LLPPAAFIPV AEESGLIVEI GNWVLTEAAR QRAEWHKRGL ADDLTLAVNV
     SPLQFKRGTV LPTLLKLQRQ YGLGSGFLEL EVTESMLMEG TERTIEDLTA IRQLGVRIAI
     DDFGTGYSSL AYLKRLPIDL IKIDRAFVKD IDRDSNDAAI CTTVVVLAHN LGVKVCAEGV
     EDAAQSAFLA SHQCDVLQGY YFSEPLLPEA VTALLERNTR FTL
//

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