(data stored in SCRATCH zone)

SWISSPROT: B2UHX2_RALPJ

ID   B2UHX2_RALPJ            Unreviewed;       253 AA.
AC   B2UHX2;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 84.
DE   RecName: Full=RNA polymerase sigma factor FliA {ECO:0000256|HAMAP-Rule:MF_00962};
DE   AltName: Full=RNA polymerase sigma factor for flagellar operon {ECO:0000256|HAMAP-Rule:MF_00962};
DE   AltName: Full=Sigma F {ECO:0000256|HAMAP-Rule:MF_00962};
DE   AltName: Full=Sigma-28 {ECO:0000256|HAMAP-Rule:MF_00962};
GN   Name=fliA {ECO:0000256|HAMAP-Rule:MF_00962};
GN   OrderedLocusNames=Rpic_4070 {ECO:0000313|EMBL:ACD29173.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29173.1, ECO:0000313|Proteomes:UP000002566};
RN   [1] {ECO:0000313|Proteomes:UP000002566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J {ECO:0000313|Proteomes:UP000002566};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor controls the expression of
CC       flagella-related genes. {ECO:0000256|HAMAP-Rule:MF_00962}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00962}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. FliA subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00962}.
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DR   EMBL; CP001069; ACD29173.1; -; Genomic_DNA.
DR   RefSeq; WP_004627728.1; NC_010678.1.
DR   STRING; 402626.Rpic_4070; -.
DR   EnsemblBacteria; ACD29173; ACD29173; Rpic_4070.
DR   GeneID; 6285420; -.
DR   KEGG; rpi:Rpic_4070; -.
DR   eggNOG; ENOG4105DN4; Bacteria.
DR   eggNOG; COG1191; LUCA.
DR   HOGENOM; HOG000270271; -.
DR   KO; K02405; -.
DR   OMA; IKFETYA; -.
DR   OrthoDB; 1857862at2; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00962; Sigma70_FliA; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR012845; RNA_pol_sigma_FliA_WhiG.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR028617; Sigma70_FliA.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02479; FliA_WhiG; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2UHX2.
DR   SWISS-2DPAGE; B2UHX2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002566};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00962};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00962,
KW   ECO:0000256|SAAS:SAAS00611263}; Lyase {ECO:0000313|EMBL:ACD29173.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002566};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00962,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00962,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00962,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN       50     63       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      213    239       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    214    233       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00962}.
FT   REGION       23     95       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00962}.
FT   REGION      103    173       Sigma-70 factor domain-3.
FT                                {ECO:0000256|HAMAP-Rule:MF_00962}.
FT   REGION      192    240       Sigma-70 factor domain-4.
FT                                {ECO:0000256|HAMAP-Rule:MF_00962}.
FT   MOTIF        50     53       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00962}.
SQ   SEQUENCE   253 AA;  28671 MW;  3CAD5A6072A246E2 CRC64;
     MNEASKAGMD MYTATGRKTK SDEMATYAPL VRRIANQMMV KLPASVELDD LIQAGMMGLL
     DALSRYEETQ GVQFEFYAAQ RIRGAILDEL RGSDWLPRGL RRNARTIEQA IQKLQQQKGR
     APTETEIAVA LGMSLAEYQK QLVDLQGSQL LYYEDFDRED ADAFIENRAP ENDATPLDQL
     LDHDLRESVV AAIEGLPERE KLMMSLYYEQ DLNLREIGAV MGVSESRVCQ IHSQAIARIR
     SRLRDRAWLP TPT
//

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