(data stored in SCRATCH zone)

SWISSPROT: B2UHX4_RALPJ

ID   B2UHX4_RALPJ            Unreviewed;       360 AA.
AC   B2UHX4;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   RecName: Full=Aldose 1-epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE            EC=5.1.3.3 {ECO:0000256|PIRNR:PIRNR005096};
DE   AltName: Full=Galactose mutarotase {ECO:0000256|PIRNR:PIRNR005096};
GN   OrderedLocusNames=Rpic_4072 {ECO:0000313|EMBL:ACD29175.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29175.1, ECO:0000313|Proteomes:UP000002566};
RN   [1] {ECO:0000313|Proteomes:UP000002566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J {ECO:0000313|Proteomes:UP000002566};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts alpha-aldose to the beta-anomer.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose = beta-D-glucose; Xref=Rhea:RHEA:10264,
CC         ChEBI:CHEBI:15903, ChEBI:CHEBI:17925; EC=5.1.3.3;
CC         Evidence={ECO:0000256|PIRNR:PIRNR005096};
CC   -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
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DR   EMBL; CP001069; ACD29175.1; -; Genomic_DNA.
DR   RefSeq; WP_012430163.1; NC_010678.1.
DR   STRING; 402626.Rpic_4072; -.
DR   EnsemblBacteria; ACD29175; ACD29175; Rpic_4072.
DR   GeneID; 6285424; -.
DR   KEGG; rpi:Rpic_4072; -.
DR   PATRIC; fig|402626.5.peg.317; -.
DR   eggNOG; ENOG4105ENN; Bacteria.
DR   eggNOG; COG2017; LUCA.
DR   HOGENOM; HOG000072798; -.
DR   KO; K01785; -.
DR   OMA; QHPHFGG; -.
DR   OrthoDB; 1512477at2; -.
DR   BioCyc; RPIC402626:GH94-4071-MONOMER; -.
DR   UniPathway; UPA00242; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR015443; Aldose_1-epimerase.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   PIRSF; PIRSF005096; GALM; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2UHX4.
DR   SWISS-2DPAGE; B2UHX4.
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002566};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR005096,
KW   ECO:0000313|EMBL:ACD29175.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002566}.
FT   ACT_SITE    190    190       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   ACT_SITE    322    322       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   BINDING     261    261       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR005096-2}.
SQ   SEQUENCE   360 AA;  38753 MW;  23C01C1B43B652CD CRC64;
     MSIAPALSAH APLDGAISSA TWGHLPDGEP VRLFTLRNAS DMRVSISDLG ATLVSWQAPD
     RGGRLGEILL NHATPAAYLQ SGGYLGGLIG RWANRIAGAR FTLDGIDYAL DRNEDSNLLH
     GGASGFHRAL WDAEEQDGAL VLRLMSAEGD AGFPGNVAVQ VRYALDDDGT LSIDYEARTD
     APTPINLTSH GYFNLSGKPG TDIRGHILSI DADAYLEVDA KLIPTRAVSV AGTAFDFRQA
     APIGVRLDWP NAQLAQAGGF DHCFMLRNTV PDDHPHVRPV ARLYEPGSGR ELTVLTDQRG
     LQFYSGHMLS GTHAQRSGLC LEASAFPNQV NMPDAEAVML RPGQVYRQRT AYRVSVARET
//

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