(data stored in SCRATCH zone)

SWISSPROT: B2UI84_RALPJ

ID   B2UI84_RALPJ            Unreviewed;       428 AA.
AC   B2UI84;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 85.
DE   SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:ACD29285.1};
GN   OrderedLocusNames=Rpic_4186 {ECO:0000313|EMBL:ACD29285.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29285.1, ECO:0000313|Proteomes:UP000002566};
RN   [1] {ECO:0000313|Proteomes:UP000002566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J {ECO:0000313|Proteomes:UP000002566};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01126420};
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DR   EMBL; CP001069; ACD29285.1; -; Genomic_DNA.
DR   RefSeq; WP_012430252.1; NC_010678.1.
DR   STRING; 402626.Rpic_4186; -.
DR   EnsemblBacteria; ACD29285; ACD29285; Rpic_4186.
DR   GeneID; 6285616; -.
DR   KEGG; rpi:Rpic_4186; -.
DR   PATRIC; fig|402626.5.peg.435; -.
DR   eggNOG; ENOG4105E0F; Bacteria.
DR   eggNOG; ENOG410XTWD; LUCA.
DR   HOGENOM; HOG000218773; -.
DR   KO; K07638; -.
DR   OMA; WIRPPQA; -.
DR   OrthoDB; 1031685at2; -.
DR   BioCyc; RPIC402626:GH94-4181-MONOMER; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; B2UI84.
DR   SWISS-2DPAGE; B2UI84.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002566};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:ACD29285.1};
KW   Membrane {ECO:0000256|SAAS:SAAS00925724, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002566};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00926038,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00926160,
KW   ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|SAAS:SAAS00924981}.
FT   TRANSMEM     12     32       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    140    164       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      164    216       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      224    425       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   428 AA;  47019 MW;  0142367B49780DF6 CRC64;
     MKFRARFDTL FGRLAVLIVV VLVLSHFSWL GVLRAERRER QFQASVDQMA FQLQAFQAAM
     DGHLHVKLPD LVTETDEPPS GDASSASDKS AELVRQLARR LPSDTQLRLE AGPTPRVFVR
     FSQRNKWIAM PLVWVHAPPS ISAVVPGVMV VLAIAIAFSL FAAWQIQRPV RELADAAGAL
     ARRRYVAPLK ERGPYELRQL TVQFNHMAAD LSAADEERNT MLAGIAHDLK TPLSRLRLRA
     EMLADQKAGA GIERDVESMS AIVEQFLAYA QSGDSEAREV SVDRHLRGLV QPFAEQGKHV
     ALDLHAGDRF RLKPTHLERI VVNLLDNAFA YGAEPVNVRT SADETGYTLT VEDHGAGIPV
     ADFDRVMRPF VRLDPARGGN AHCGLGLAIV DRLVRHLGGD LTVGPTATDA PSPGFRVTMR
     FPVSTAAA
//

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