(data stored in ACNUC23405 zone)

SWISSPROT: B3DHA2_DANRE

ID   B3DHA2_DANRE            Unreviewed;       309 AA.
AC   B3DHA2;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   07-SEP-2016, entry version 67.
DE   SubName: Full=Homeo box HB9 like a {ECO:0000313|EMBL:AAI62692.1};
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000061715};
GN   Name=mnx2a {ECO:0000313|Ensembl:ENSDARP00000061715,
GN   ECO:0000313|ZFIN:ZDB-GENE-040415-1};
GN   Synonyms=hlxb9la {ECO:0000313|EMBL:AAI62692.1,
GN   ECO:0000313|ZFIN:ZDB-GENE-040415-1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI62692.1};
RN   [1] {ECO:0000313|EMBL:AAI62692.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000061715}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000061715};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000061715, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000061715,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000682,
CC       ECO:0000256|SAAS:SAAS00544279}.
CC   -!- SIMILARITY: Contains homeobox DNA-binding domain.
CC       {ECO:0000256|SAAS:SAAS00349485}.
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DR   EMBL; CU693367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC162692; AAI62692.1; -; mRNA.
DR   EMBL; BC162717; AAI62717.1; -; mRNA.
DR   RefSeq; NP_001009886.2; NM_001009886.2.
DR   UniGene; Dr.91916; -.
DR   STRING; 7955.ENSDARP00000061715; -.
DR   Ensembl; ENSDART00000061716; ENSDARP00000061715; ENSDARG00000042106.
DR   GeneID; 406205; -.
DR   KEGG; dre:406205; -.
DR   CTD; 406205; -.
DR   ZFIN; ZDB-GENE-040415-1; mnx2a.
DR   eggNOG; KOG0489; Eukaryota.
DR   eggNOG; ENOG410ZTBY; LUCA.
DR   GeneTree; ENSGT00760000118940; -.
DR   HOGENOM; HOG000234345; -.
DR   HOVERGEN; HBG051910; -.
DR   KO; K08025; -.
DR   OMA; CKRTENS; -.
DR   OrthoDB; EOG091G0OTP; -.
DR   TreeFam; TF351530; -.
DR   Proteomes; UP000000437; Chromosome 9.
DR   Bgee; ENSDARG00000042106; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:ZFIN.
DR   Gene3D; 1.10.10.60; -; 1.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR009057; Homeodomain-like.
DR   Pfam; PF00046; Homeobox; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; B3DHA2.
DR   SWISS-2DPAGE; B3DHA2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   DNA-binding {ECO:0000256|RuleBase:RU000682,
KW   ECO:0000256|SAAS:SAAS00427301};
KW   Homeobox {ECO:0000256|RuleBase:RU000682,
KW   ECO:0000256|SAAS:SAAS00427317};
KW   Nucleus {ECO:0000256|RuleBase:RU000682,
KW   ECO:0000256|SAAS:SAAS00427283};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN      148    208       Homeobox DNA-binding.
FT                                {ECO:0000259|PROSITE:PS50071}.
SQ   SEQUENCE   309 AA;  34552 MW;  5206B7E49D1AE608 CRC64;
     MDKSKNFRID ALLSESSQQI VRGDSPGLCS EGVDVDMCKR TENSLPRAFQ LQTGVIPKPG
     MLNISHPGLT SLSQGSMPGM YPSPMYSITA LGAQHPSFAY SGFTQPYPDH LKAAAMAGSL
     PLEHWLRAGL IMPRLADYSG APQSGLIGKC RRPRTAFTSQ QLLELENQFK LNKYLSRPKR
     FEVATSLMLT ETQVKIWFQN RRMKWKRSRK AKEQAAQLET DGCKSGKRGN KPKDLSRCSA
     HDEDEDLDPE EEAEEDEEEF RRSINVGVSL PRHSDFLQHS SALSYSSHGS YSDDDLEEIG
     ADRKIRLGL
//

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