(data stored in ACNUC9543 zone)

SWISSPROT: A0A384LNP1_PLAKH

ID   A0A384LNP1_PLAKH        Unreviewed;      1218 AA.
AC   A0A384LNP1; A0A1A7VVC4; B3L263;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   08-MAY-2019, entry version 5.
DE   SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22, putative {ECO:0000313|EMBL:SBO25913.1};
DE   SubName: Full=RNA helicase, putative {ECO:0000313|EMBL:CAQ38982.1};
GN   ORFNames=PKH_061440 {ECO:0000313|EMBL:CAQ38982.1}, PKNA1_C2_0614800
GN   {ECO:0000313|EMBL:SBO23961.1}, PKNA1_H1_0614800
GN   {ECO:0000313|EMBL:SBO25913.1};
OS   Plasmodium knowlesi (strain H).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5851 {ECO:0000313|EMBL:SBO25913.1};
RN   [1] {ECO:0000313|EMBL:CAQ38982.1, ECO:0000313|Proteomes:UP000031513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H {ECO:0000313|EMBL:CAQ38982.1,
RC   ECO:0000313|Proteomes:UP000031513};
RA   Pain A., Boehme U., Berry A.E., Mungall K., Finn R., Jackson A.P.,
RA   Mourier T., Mistry J., Pasini E.M., Aslett M., Balasubrammaniam S.,
RA   Borgwardt K., Brooks K., Carret C., Carver T.J., Cherevach I.,
RA   Chillingworth T., Clarke T.G., Galinski M.R., Hall N., Harper D.,
RA   Harris D., Hauser H., Ivens A., Janssen C.S., Keane T., Larke N.,
RA   Lapp S., Marti M., Moule S., Meyer I.M., Ormond D., Peters N.,
RA   Sanders M., Sanders S., Sergeant T.J., Simmonds M., Smith F.,
RA   Squares R., Thurston S., Tivey A.R., Walker D., White B.,
RA   Zuiderwijk E., Churcher C., Quail M.A., Cowman A.F., Turner C.M.R.,
RA   Rajandream M.A., Kocken C.H.M., Thomas A.W., Newbold C.I.,
RA   Barrell B.G., Berriman M.;
RT   "The genome of Plasmodium knowlesi strain H, a zoonotic malaria
RT   parasite with host range from monkey to man.";
RL   Nature 455:799-803(2008).
RN   [2] {ECO:0000313|EMBL:SBO25913.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lavstsen T., Jespersen J.S.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM910988; CAQ38982.1; -; Genomic_DNA.
DR   EMBL; CWHQ02000009; SBO23961.1; -; Genomic_DNA.
DR   EMBL; CWHR02000008; SBO25913.1; -; Genomic_DNA.
DR   RefSeq; XP_002261819.1; XM_002261783.1.
DR   GeneID; 7319629; -.
DR   KEGG; pkn:PKH_061440; -.
DR   HOGENOM; HOG000175261; -.
DR   KO; K12818; -.
DR   Proteomes; UP000031513; Chromosome 6.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
DR   PRODOM; A0A384LNP1.
DR   SWISS-2DPAGE; A0A384LNP1.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01176619};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031513};
KW   Helicase {ECO:0000313|EMBL:SBO25913.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01176622};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01176608};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031513}.
FT   DOMAIN      245    320       S1 motif. {ECO:0000259|PROSITE:PS50126}.
FT   DOMAIN      569    732       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      755    931       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
SQ   SEQUENCE   1218 AA;  140099 MW;  6491E2AB96332807 CRC64;
     MECLSKINLI QKVNAELYKS LGVEDDNLAE YLIYLCKKAK SLEEFCKEVF ENGGEIEQSV
     LKYLYDIIKI PDGESGGKAS GGKENRTDDT EEEEEDGVDK EKRLEMKMIE KKNEKMKRFH
     CLTIKNDEQL TRLSEGSGLE GGSDTATGGG RSRKRSHHRD GHSNGDRDDS QDGSHIHGKD
     RHDRRSRYED KSRHEDRSHR EDRLRHRDGH RHREEHHRRD RSHSREGDHK RRRREGAESF
     ALRVNNIFSG KVSKIMDFGM FVSFRTEPGG YKEGLVHCTD ILPNRKRVVN MSEKFQKGMK
     VKVKVKAIFG EKINLNMSEV DQKTGKDLVS DYEEDSHRGE NSYGKEGQKN VMSIFDDLHE
     DYKELKKHNS DVFKEDVKDT MKYESVIKMQ SDYAKWEIQQ LIKGGIMYDE EIKKEYKNLR
     NDEKIEDEEE IIEIEVNEKE PSFLKGQTTK AGAKLSPIQV IVNAEGSLAR AITTTCALAK
     ERKEQKQNEQ NAIYDSIPKD ISRPWEDPKP ELGERTIAEA LKNIGKNYDL PEWRKNYLHN
     NISIGVKNPM PVNEQREKLP IYHLKKDLMK AIAKNNVLIV IGETGSGKTT QIPQYLHEAN
     YTDKGIVGCT QPRRVAAMSI AKRVSEEFGC ILGQEVGYSI RFDDCTSNDT IIKYLTDGML
     LRETLSDTML SKYSFIILDE AHERTISTDI LFCLLKDVVK RRPDFKLIVT SATLDAEKFS
     TYFFNSPIFT IPGKIFPVEI LHSKEPESDY VEACLITVLN IHLNEHPGDI LVFLTGQDEI
     NTACEILHER MKKLESMSPP PLIILPIYSS LPSEMQSVIF DPAPQGCRKC VLATNIAEAS
     LTIDGIFFVI DPGFCKIRKY DSKRDMDSLV VAPISKANAK QRAGRAGRTG PGKCYRLYTE
     DAYKNEMAET SIPEIQRINL GSTVLLLKAL GVNDFLHFDF MDSPSVDTLI HSLENLYYLG
     ALDDNGYLTK LGKKMSNFPM EPTLSKILLT SINFNCADDV VTIVSMLSVQ NIFYRPQNKA
     LLADKKKNKF IMPQGDLITY LNIYNRWREN NYSNYWCHEN FIHSRALRRS QDVRKQILSI
     FERYNYEVEK NKSRNDSAKY VSICKSICSG YFSHVCKRDA QQGYTTLLTN QQVFIHPSST
     LFNKNPLFVV YHELVLTNKE YIRDCTIIQP QWLIQLAPNL FIPADEKKIS KIKLREKIEP
     LHNYYEEPNA WRLSRRKG
//

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