(data stored in SCRATCH zone)

SWISSPROT: B4SJ42_STRM5

ID   B4SJ42_STRM5            Unreviewed;       185 AA.
AC   B4SJ42;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   08-MAY-2019, entry version 60.
DE   RecName: Full=dTDP-4-dehydrorhamnose 3,5-epimerase {ECO:0000256|RuleBase:RU364069};
DE            EC=5.1.3.13 {ECO:0000256|RuleBase:RU364069};
DE   AltName: Full=Thymidine diphospho-4-keto-rhamnose 3,5-epimerase {ECO:0000256|RuleBase:RU364069};
GN   OrderedLocusNames=Smal_0505 {ECO:0000313|EMBL:ACF50210.1};
OS   Stenotrophomonas maltophilia (strain R551-3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas;
OC   Stenotrophomonas maltophilia group.
OX   NCBI_TaxID=391008 {ECO:0000313|EMBL:ACF50210.1, ECO:0000313|Proteomes:UP000001867};
RN   [1] {ECO:0000313|EMBL:ACF50210.1, ECO:0000313|Proteomes:UP000001867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R551-3 {ECO:0000313|EMBL:ACF50210.1,
RC   ECO:0000313|Proteomes:UP000001867};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L.,
RA   Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Taghavi S., Monchy S., Newman L., Vangronsveld J.,
RA   van der Lelie D., Richardson P.;
RT   "Complete sequence of Stenotrophomonas maltophilia R551-3.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the epimerization of the C3' and C5'positions
CC       of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-
CC       hexulose. {ECO:0000256|RuleBase:RU364069}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-
CC         beta-L-rhamnose; Xref=Rhea:RHEA:16969, ChEBI:CHEBI:57649,
CC         ChEBI:CHEBI:62830; EC=5.1.3.13;
CC         Evidence={ECO:0000256|RuleBase:RU364069};
CC   -!- PATHWAY: Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.
CC       {ECO:0000256|RuleBase:RU364069}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU364069}.
CC   -!- SIMILARITY: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase
CC       family. {ECO:0000256|RuleBase:RU364069}.
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DR   EMBL; CP001111; ACF50210.1; -; Genomic_DNA.
DR   RefSeq; WP_012509982.1; NC_011071.1.
DR   STRING; 391008.Smal_0505; -.
DR   EnsemblBacteria; ACF50210; ACF50210; Smal_0505.
DR   KEGG; smt:Smal_0505; -.
DR   eggNOG; ENOG4108URP; Bacteria.
DR   eggNOG; COG1898; LUCA.
DR   HOGENOM; HOG000227724; -.
DR   KO; K01790; -.
DR   OMA; RSILWND; -.
DR   OrthoDB; 1618609at2; -.
DR   BioCyc; SMAL391008:SMAL_RS02585-MONOMER; -.
DR   UniPathway; UPA00124; -.
DR   Proteomes; UP000001867; Chromosome.
DR   GO; GO:0008830; F:dTDP-4-dehydrorhamnose 3,5-epimerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019305; P:dTDP-rhamnose biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR000888; dTDP_sugar_isom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR21047; PTHR21047; 1.
DR   Pfam; PF00908; dTDP_sugar_isom; 1.
DR   ProDom; PD001462; dTDP_sugar_isom; 1.
DR   SUPFAM; SSF51182; SSF51182; 1.
DR   TIGRFAMs; TIGR01221; rmlC; 1.
PE   3: Inferred from homology;
DR   PRODOM; B4SJ42.
DR   SWISS-2DPAGE; B4SJ42.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001867};
KW   Isomerase {ECO:0000256|RuleBase:RU364069,
KW   ECO:0000313|EMBL:ACF50210.1}.
SQ   SEQUENCE   185 AA;  20652 MW;  ED939AAB56207B6A CRC64;
     MKVIETRLPG CVVIEPAVFG DARGYFFETW NAERFAALGL PHRFAQSNVS TSAQGVLRGL
     HYQWPRPQGK LVSVLEGEVY DVAVDIRRGS PTFGQWEAVV LSAENKKQFW IPDGFAHGFA
     VLSERAVFSY LCTEVYLKDF DAGVRWNDAD IAVDWPISAP TLSAKDESAP FLKDIAEDRL
     PVYVP
//

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