(data stored in SCRATCH zone)

SWISSPROT: B6H1Y4_PENRW

ID   B6H1Y4_PENRW            Unreviewed;       850 AA.
AC   B6H1Y4;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 49.
DE   SubName: Full=Pc13g03370 protein {ECO:0000313|EMBL:CAP91406.1};
GN   ORFNames=Pc13g03370 {ECO:0000313|EMBL:CAP91406.1}, PCH_Pc13g03370
GN   {ECO:0000313|EMBL:CAP91406.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP91406.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP91406.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- SIMILARITY: Belongs to the peptidase C2 family.
CC       {ECO:0000256|SAAS:SAAS00586566}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM920428; CAP91406.1; -; Genomic_DNA.
DR   RefSeq; XP_002558775.1; XM_002558729.1.
DR   STRING; 500485.XP_002558775.1; -.
DR   MEROPS; C02.008; -.
DR   EnsemblFungi; CAP91406; CAP91406; PCH_Pc13g03370.
DR   GeneID; 8313437; -.
DR   KEGG; pcs:Pc13g03370; -.
DR   eggNOG; KOG0045; Eukaryota.
DR   eggNOG; ENOG410XP0B; LUCA.
DR   HOGENOM; HOG000212111; -.
DR   OMA; HYTVRVY; -.
DR   OrthoDB; EOG092C185F; -.
DR   BioCyc; PCHR:PC13G03370-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c13.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR   CDD; cd00044; CysPc; 1.
DR   InterPro; IPR022684; Calpain_cysteine_protease.
DR   InterPro; IPR022682; Calpain_domain_III.
DR   InterPro; IPR022683; Calpain_III.
DR   InterPro; IPR007330; MIT.
DR   InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR   Pfam; PF01067; Calpain_III; 1.
DR   Pfam; PF00648; Peptidase_C2; 1.
DR   PRINTS; PR00704; CALPAIN.
DR   SMART; SM00720; calpain_III; 1.
DR   SMART; SM00230; CysPc; 1.
DR   SMART; SM00745; MIT; 1.
DR   SUPFAM; SSF49758; SSF49758; 2.
DR   PROSITE; PS50203; CALPAIN_CAT; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6H1Y4.
DR   SWISS-2DPAGE; B6H1Y4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00239};
KW   Protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Thiol protease {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT   DOMAIN      126    437       Calpain catalytic. {ECO:0000259|PROSITE:
FT                                PS50203}.
FT   ACT_SITE    197    197       {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT   ACT_SITE    364    364       {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT   ACT_SITE    384    384       {ECO:0000256|PROSITE-ProRule:PRU00239}.
SQ   SEQUENCE   850 AA;  93875 MW;  FE529D9B536C5C39 CRC64;
     MSRPASTQSL ISQARSAEEA IAAATSKKAA LEAAINAAEH YMKALRLAPA DDKKLLDAKC
     KELISKAEKI KAATDWQSAA RAGPQKAFPS LRPPASTRKL TTREEIIILE GAKLNGYIFP
     PWSRAPPQDE FVYKGQLFTD TPDLHLSECQ REIFAGWKRP HDLLQTMNTA KQPYDIINPA
     MSASGETDLV QDVLTDCSVV ASLCATTARS ERGLGQHASP TLYPCSEDKN PILSHSGKYI
     FRFYFNGSFR KVVIDDRLPS SKTTRSLHVI DRNNSNFLWP ALVEKAYLKV RGGYDFPGSN
     SGTDLWVLTG WIPEQVFLHH DDSTSDEIWG RLYSAFWHGD VVLTIGTGKL TELEQQGLGL
     VSEHDYAILD LKEVQGRRQF LLKNPWAGAE PHIQSSLTAD LGSLGLNDKP PLSPGTFWMD
     CEQVLQNFEN LYLNWNPGLF KYREDIHFTW DLSHGRVIAG CFVKNPQFSI SSDSGGTVWL
     LLGKHFKTDH QEFDTGESEN ETGFISIYIF QADGRRVSLS DGALHRGPYV DSPNTLMRLE
     MPPKSTYTAV VSEQSLPSSA QNFTLSAFST APVAVAPSLD KYLCLTKASG SWTAMTAGGN
     AESPRYHSNP QFSIRISEPT DVSILLETTE AELATHVKIF WSNGQRVSRV RSRDIIADSG
     DYRRGCALAE TKSLDKGTYT IVCSTFAPDQ FGRFTLWISS TIPCVVQPLV SESAGRRAVL
     SEVGVLSPGK DRMLASLRVS RLTRIRLIAR NKRSTVGLRA VAPSPVLMTV ELGQGPYKEI
     LATSEDGAHS DAASGVRVED FDLLPSAESR RVWIVIERIG GPGGQVEDHF EVEALAEERV
     EIGKWVIEDE
//

If you have problems or comments...

PBIL Back to PBIL home page