(data stored in SCRATCH zone)

SWISSPROT: B6H7I2_PENRW

ID   B6H7I2_PENRW            Unreviewed;       455 AA.
AC   B6H7I2;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 48.
DE   RecName: Full=Mannan endo-1,6-alpha-mannosidase {ECO:0000256|PIRNR:PIRNR016302};
DE            EC=3.2.1.101 {ECO:0000256|PIRNR:PIRNR016302};
GN   ORFNames=Pc16g02660 {ECO:0000313|EMBL:CAP92936.1}, PCH_Pc16g02660
GN   {ECO:0000313|EMBL:CAP92936.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP92936.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP92936.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- CATALYTIC ACTIVITY: Random hydrolysis of (1->6)-alpha-D-mannosidic
CC       linkages in unbranched (1->6)-mannans.
CC       {ECO:0000256|PIRNR:PIRNR016302}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 76 family.
CC       {ECO:0000256|PIRNR:PIRNR016302}.
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DR   EMBL; AM920431; CAP92936.1; -; Genomic_DNA.
DR   RefSeq; XP_002560638.1; XM_002560592.1.
DR   ProteinModelPortal; B6H7I2; -.
DR   CAZy; GH76; Glycoside Hydrolase Family 76.
DR   EnsemblFungi; CAP92936; CAP92936; PCH_Pc16g02660.
DR   GeneID; 8307047; -.
DR   KEGG; pcs:Pc16g02660; -.
DR   eggNOG; ENOG410IE3C; Eukaryota.
DR   eggNOG; ENOG410XTMT; LUCA.
DR   HOGENOM; HOG000178818; -.
DR   KO; K08257; -.
DR   OMA; MSEVLCE; -.
DR   OrthoDB; EOG092C22S6; -.
DR   BioCyc; PCHR:PC16G02660-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008496; F:mannan endo-1,6-alpha-mannosidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR   InterPro; IPR008928; 6-hairpin_glycosidase-like.
DR   InterPro; IPR005198; Glyco_hydro_76.
DR   InterPro; IPR014480; Mannan-1_6-alpha_mannosidase.
DR   PANTHER; PTHR12145; PTHR12145; 1.
DR   Pfam; PF03663; Glyco_hydro_76; 1.
DR   PIRSF; PIRSF016302; Man_a_manosd; 1.
DR   SUPFAM; SSF48208; SSF48208; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6H7I2.
DR   SWISS-2DPAGE; B6H7I2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Glycosidase {ECO:0000256|PIRNR:PIRNR016302};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR016302};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    455       Mannan endo-1,6-alpha-mannosidase.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002845482.
FT   TRANSMEM    431    453       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   455 AA;  50158 MW;  26E0F93B9BE94703 CRC64;
     MRLSGTWSIS NGLIATLLFS TLTPAIELDL NDEQSIKDAA STSTYSMMGW YYGNETGQIP
     GSFPEKWWEG SALFLALLQY WHFTGDTTYN SLMSEGMQWQ SGEEGDYMPS NYSSYLGNDD
     QMFWGLAAMM AAELKFPDVE DGFSWLSLAQ GVFNTQTARW DTTTCGGGLR WQLFPYQSGY
     TMKNSVSNGG LFQLAARLAR YTDDDKYSKW AEKIWDWSTS SPLVNNKTWN VADSTQMAND
     CADSGNYQWT YNYGAYLMGA VYMYNYTNGD EKWKKPVDGL LGKTLKTFFP NGDVIEDVTC
     EPIKMCNFNE ILFKGLTSSW LAFTTLLAPD TAAQIKPKLA SSAEAAAKSC TGNNNNTCGI
     TWYQNKWDGT TGMEQEISAT NVFLANLINY NTGSFGPVTS KTGGNSASDP NAGSENDDEK
     KMKPITTGDK AGASILTLIF VFGWAGAVAF MMLGG
//

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