(data stored in SCRATCH zone)

SWISSPROT: B6HH67_PENRW

ID   B6HH67_PENRW            Unreviewed;      1206 AA.
AC   B6HH67;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=Coatomer subunit alpha {ECO:0000256|PIRNR:PIRNR003354};
GN   ORFNames=Pc20g03970 {ECO:0000313|EMBL:CAP85726.1}, PCH_Pc20g03970
GN   {ECO:0000313|EMBL:CAP85726.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85726.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP85726.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: The coatomer is a cytosolic protein complex that binds
CC       to dilysine motifs and reversibly associates with Golgi non-
CC       clathrin-coated vesicles, which further mediate biosynthetic
CC       protein transport from the ER, via the Golgi up to the trans Golgi
CC       network. {ECO:0000256|PIRNR:PIRNR003354}.
CC   -!- SUBUNIT: Oligomeric complex that consists of at least the alpha,
CC       beta, beta', gamma, delta, epsilon and zeta subunits.
CC       {ECO:0000256|PIRNR:PIRNR003354}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR003354}.
CC       Golgi apparatus membrane {ECO:0000256|PIRNR:PIRNR003354};
CC       Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR003354}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM920435; CAP85726.1; -; Genomic_DNA.
DR   RefSeq; XP_002562947.1; XM_002562901.1.
DR   ProteinModelPortal; B6HH67; -.
DR   STRING; 500485.XP_002562947.1; -.
DR   EnsemblFungi; CAP85726; CAP85726; PCH_Pc20g03970.
DR   GeneID; 8310002; -.
DR   KEGG; pcs:Pc20g03970; -.
DR   eggNOG; KOG0292; Eukaryota.
DR   eggNOG; ENOG410XPZS; LUCA.
DR   HOGENOM; HOG000195913; -.
DR   KO; K05236; -.
DR   OMA; AGHDNGV; -.
DR   OrthoDB; EOG092C10HM; -.
DR   BioCyc; PCHR:PC20G03970-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0030126; C:COPI vesicle coat; IEA:UniProtKB-UniRule.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 2.120.10.30; -; 1.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR016391; Coatomer_asu.
DR   InterPro; IPR010714; Coatomer_asu_C.
DR   InterPro; IPR006692; Coatomer_WD-assoc_reg.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR011044; Quino_amine_DH_bsu.
DR   InterPro; IPR011990; TPR-like_helical_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   Pfam; PF04053; Coatomer_WDAD; 1.
DR   Pfam; PF06957; COPI_C; 1.
DR   Pfam; PF00400; WD40; 5.
DR   PIRSF; PIRSF003354; Coatomer_alpha_subunit; 1.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50969; SSF50969; 1.
DR   SUPFAM; SSF50978; SSF50978; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
DR   PRODOM; B6HH67.
DR   SWISS-2DPAGE; B6HH67.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR003354};
KW   ER-Golgi transport {ECO:0000256|PIRNR:PIRNR003354};
KW   Golgi apparatus {ECO:0000256|PIRNR:PIRNR003354};
KW   Membrane {ECO:0000256|PIRNR:PIRNR003354};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR003354};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Repeat {ECO:0000256|SAAS:SAAS00780417};
KW   Transport {ECO:0000256|PIRNR:PIRNR003354};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221,
KW   ECO:0000256|SAAS:SAAS00775705}.
FT   DOMAIN        5    331       WD_REPEATS_REGION. {ECO:0000259|PROSITE:
FT                                PS50294}.
FT   REPEAT       47     88       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   REPEAT       89    130       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   REPEAT      131    172       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   REPEAT      205    246       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   REPEAT      249    290       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
SQ   SEQUENCE   1206 AA;  135329 MW;  997DCBB9819D83C2 CRC64;
     MLTKFESKSS RAKGIAFHPK RPWILVSLHS STIQLWDYRM GTLIDRFEEH DGPVRGVDFH
     PTQPLFVSGG DDYKIKVWNY QTRRCLFTLN GHLDYVRTVF FHPELPWILS ASDDQTIRIW
     NWQNRSLICT MTGHNHYVMC AQFHPTEDLI ASASLDQSVR IWDISGLRKK HSAPTSISFE
     DQMARANPNQ ADMFGNTDAV VKFVLEGHDR GVNWVSFHPT LPLLVSAGDD RLVKLWRMSD
     TKAWEVDTCR GHFQNASAAL FHPHQDLILS VGEDKTIRAW DLNKRTSVQS FKRDLDRFWV
     IAAHPEMNLF AAGHDTGVMV FKLERERPAS AIYQNQLFYI TKDKHVKSYD FAKNVESPPM
     LSLRKLGSPW VPPRTLSYNP AERAILVTSP ADNGTYELIH LPRDATGAVE PTDVKRGQAT
     SAVFVARNRF AVFNPSSQQV DIKDLSNSTT KTIKPPAGTT DIYFGGTGCL LFITPTHVAL
     FDIQQKKQLA ELAVSGVKYV VWSNDGLYCA LLSKHNVTIV TKTLEQVSTL HETIRIKSAT
     WDDAGVLLYS TLNHVKYSLL NGDNGIIRTL DQTVYLVRVK GRSVYALDRN AQPRILEIDP
     TEYRFKLALV KRNYDEMLQI IKTSSLVGQS IISYLQKKGY PEIALQFVQD PQTRFDLALE
     CGNLEVANEM ARELERPKIW SRLGAEALAH GNHQIVEMTY QKQRNFDKLS FLYLSTGDEE
     KLARMAKIAE HRGDFTSRFQ NAIYRGDVED RIQMFKEVDL YPLAYLTAKS HGLIEEAESI
     LEAVGLTEDQ IVLPTLEQPL KVPHPIVPTF QSNWPVKAAG HSSFEKALLG EVGVDEEAGA
     DGFDIEEEEQ EAAVARETLD EDEEEVSGWD MGDDVNVEEE VDFVNVESAE AGAGSSEADL
     WARNSPLAAD HVAAGSFDTA MQLLNRQVGA VQFAPLKARF LEVYKASKTY LPATAGLPPL
     VNYVRRTVDE TELRKMLPII PRDLETVASV DLQEGYAAMR SNKLEDGVAT FKRILHTVLV
     NTVSSEAEVE EAKKIIATAR EYILAMSIEL ERRSLTTDSP DNLKRSLELS AYFTIPKLEV
     AHRQLALMAA MKLAFANKNY GSALSFANRM LANGGSAKLL EQAKKIKAQC ERNPQDQIDI
     DFDPFAEFDI CAASYTPIYS GSPSVSDPFT GAKYHPQYKG SVDRISDVTE IGAPASGLRL
     FVPSQF
//

If you have problems or comments...

PBIL Back to PBIL home page