(data stored in SCRATCH zone)

SWISSPROT: B7UIA2_ECO27

ID   B7UIA2_ECO27            Unreviewed;       784 AA.
AC   B7UIA2;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 61.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411, ECO:0000256|SAAS:SAAS00073013};
DE   Flags: Precursor;
GN   Name=imp {ECO:0000313|EMBL:CAS07605.1};
GN   Synonyms=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN   OrderedLocusNames=E2348C_0057 {ECO:0000313|EMBL:CAS07605.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS07605.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS07605.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000256|HAMAP-Rule:MF_01411, ECO:0000256|SAAS:SAAS00542435}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and
CC       assembly complex. Interacts with LptE and LptA.
CC       {ECO:0000256|HAMAP-Rule:MF_01411, ECO:0000256|SAAS:SAAS00542429}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01411, ECO:0000256|SAAS:SAAS00073022}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC       Rule:MF_01411, ECO:0000256|SAAS:SAAS00542431}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
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DR   EMBL; FM180568; CAS07605.1; -; Genomic_DNA.
DR   RefSeq; WP_000746165.1; NC_011601.1.
DR   EnsemblBacteria; CAS07605; CAS07605; E2348C_0057.
DR   KEGG; ecg:E2348C_0057; -.
DR   HOGENOM; HOG000218450; -.
DR   KO; K04744; -.
DR   OMA; DYSHLDW; -.
DR   BioCyc; ECOL574521:E2348C_RS00295-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; OstA; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UIA2.
DR   SWISS-2DPAGE; B7UIA2.
KW   Cell outer membrane {ECO:0000256|HAMAP-Rule:MF_01411,
KW   ECO:0000256|SAAS:SAAS00425687};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01411,
KW   ECO:0000256|SAAS:SAAS00073016};
KW   Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT   SIGNAL        1     24       {ECO:0000256|HAMAP-Rule:MF_01411}.
FT   CHAIN        25    784       LPS-assembly protein LptD.
FT                                {ECO:0000256|HAMAP-Rule:MF_01411}.
FT                                /FTId=PRO_5009008042.
FT   DOMAIN       53    194       OstA-like_N. {ECO:0000259|Pfam:PF03968}.
FT   DOMAIN      309    697       LptD. {ECO:0000259|Pfam:PF04453}.
SQ   SEQUENCE   784 AA;  89667 MW;  C44F47A9122F6A1D CRC64;
     MKKRIPTLLA TMIATALYSQ QGLAADLASQ CMLGVPSYDR PLVQGDTNDL PVTINADHAK
     GDYPDDAVFT GSVDIMQGNS RLQADEVQLH QKEAPGQPEP VRTVDALGNV HYDDNQVILK
     GPKGWANLNT KDTNVWEGDY QMVGRQGRGK ADLMKQRGEN RYTILDNGSF TSCLPGSDTW
     SVVGSEIIHD REEQVAEIWN ARFKVGPVPI FYSPYLQLPV GDKRRSGFLI PNAKYTTTNY
     FEFYLPYYWN IAPNMDATIT PHYMHRRGNI MWENEFRYLS QAGAGLMELD YLPSDKVYKD
     EHPNDDSSRR WLFYWKHSGV MDQVWRFNVD YTKVSDPSYF NDFDNKYGSS TDGYATQKFS
     VGYAVQNFNA TVSTKQFQVF SEQNTSSYSA EPQLDVNYYQ NDVGPFDTRI YGQAVHFVNT
     RDDMPEATRV HLEPTINLPL SNNWGSINTE AKLLATHYQQ TNLDWYNSRN TTRLAESANR
     VMPQFKVDGR MVFERDMEML APGYTQTLEP RAQYLYVPYR DQSKIYNYDS SLLQSDYSGL
     FRDRTYGGLD RIASANQVTT GVTSRIYDDA AVERFNISVG QIYYFTESRT GDDNITWEND
     DKTGSLVWAG DTYWRISDRW GLRGGIQYDT RLDNVATSNS SIEYRRDEDR LVQLNYRYAS
     PEYIQATLPK YYSTAEQYKN GISQVGAVAS WPIADRWSIV GAYYYDTNAN KQADSMLGVQ
     YSSCCYAIRV GYERKLNGWD NDKQHAVYDN AIGFNIELRG LSSNYGLGTQ EMLRSNILPY
     QNTL
//

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