(data stored in SCRATCH zone)

SWISSPROT: B7UIB7_ECO27

ID   B7UIB7_ECO27            Unreviewed;       232 AA.
AC   B7UIB7;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Thiamine import ATP-binding protein ThiQ {ECO:0000256|HAMAP-Rule:MF_01723};
DE            EC=3.6.3.- {ECO:0000256|HAMAP-Rule:MF_01723};
GN   Name=thiQ {ECO:0000256|HAMAP-Rule:MF_01723,
GN   ECO:0000313|EMBL:CAS07620.1};
GN   OrderedLocusNames=E2348C_0072 {ECO:0000313|EMBL:CAS07620.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS07620.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS07620.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Part of the ABC transporter complex ThiBPQ involved in
CC       thiamine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000256|HAMAP-Rule:MF_01723}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (ThiQ), two transmembrane proteins (ThiP) and a solute-binding
CC       protein (ThiB). {ECO:0000256|HAMAP-Rule:MF_01723}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01723}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01723}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Thiamine
CC       importer (TC 3.A.1.19.1) family. {ECO:0000256|HAMAP-
CC       Rule:MF_01723}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FM180568; CAS07620.1; -; Genomic_DNA.
DR   RefSeq; WP_000916297.1; NC_011601.1.
DR   EnsemblBacteria; CAS07620; CAS07620; E2348C_0072.
DR   KEGG; ecg:E2348C_0072; -.
DR   KO; K02062; -.
DR   OMA; TSHYPSE; -.
DR   BioCyc; ECOL574521:E2348C_RS00370-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0048502; F:thiamine-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071934; P:thiamine transmembrane transport; IEA:InterPro.
DR   GO; GO:0015888; P:thiamine transport; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005968; Thiamine_ABC_ThiQ.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01277; thiQ; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51288; THIQ; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UIB7.
DR   SWISS-2DPAGE; B7UIB7.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01723, ECO:0000256|PROSITE-
KW   ProRule:PRU00434};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01723};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01723,
KW   ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01723}.
FT   DOMAIN        2    230       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      32     39       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   232 AA;  25004 MW;  ADC960EC37C7940D CRC64;
     MLKLTDITWL YHHLPMRFSL TVERGEQVAI LGPSGAGKST LLNLIAGFLT PASGSLTIDG
     VDHTTTPPSR RPVSMLFQEN NLFSHLTVAQ NIGLGLNPGL KLNAAQQKKM HAIAHQMGID
     NLMARLPGEL SGGQRQRVAL ARCLVREQPI LLLDEPFSAL DPALRQEMLT LVSSSCQQQK
     MTLLMVSHSV EDAARIATRS VVVADGRIAW QGKTDELLSG KASASALLGI KG
//

If you have problems or comments...

PBIL Back to PBIL home page