(data stored in SCRATCH zone)

SWISSPROT: B7UJA1_ECO27

ID   B7UJA1_ECO27            Unreviewed;       343 AA.
AC   B7UJA1;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   RecName: Full=Methionine import ATP-binding protein MetN {ECO:0000256|HAMAP-Rule:MF_01719};
DE            EC=3.6.3.- {ECO:0000256|HAMAP-Rule:MF_01719};
GN   Name=metN {ECO:0000256|HAMAP-Rule:MF_01719,
GN   ECO:0000313|EMBL:CAS07753.1};
GN   OrderedLocusNames=E2348C_0205 {ECO:0000313|EMBL:CAS07753.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS07753.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS07753.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Part of the ABC transporter complex MetNIQ involved in
CC       methionine import. Responsible for energy coupling to the
CC       transport system. {ECO:0000256|HAMAP-Rule:MF_01719,
CC       ECO:0000256|SAAS:SAAS01165801}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (MetN), two transmembrane proteins (MetI) and a solute-binding
CC       protein (MetQ). {ECO:0000256|HAMAP-Rule:MF_01719,
CC       ECO:0000256|SAAS:SAAS01165800}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01719}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01719}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Methionine
CC       importer (TC 3.A.1.24) family. {ECO:0000256|HAMAP-Rule:MF_01719,
CC       ECO:0000256|SAAS:SAAS00548293}.
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DR   EMBL; FM180568; CAS07753.1; -; Genomic_DNA.
DR   RefSeq; WP_000593994.1; NC_011601.1.
DR   SMR; B7UJA1; -.
DR   EnsemblBacteria; CAS07753; CAS07753; E2348C_0205.
DR   KEGG; ecg:E2348C_0205; -.
DR   KO; K02071; -.
DR   OMA; LIRLINC; -.
DR   BioCyc; ECOL574521:E2348C_RS01055-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015424; F:amino acid-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0048474; F:D-methionine transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd03258; ABC_MetN_methionine_transporte; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR026253; ABC_MetN.
DR   InterPro; IPR012692; ABC_MetN_proteobac.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR017908; ABC_transprt_methionine_MetN_C.
DR   InterPro; IPR041701; MetN_ABC.
DR   InterPro; IPR018449; NIL_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43166:SF5; PTHR43166:SF5; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF09383; NIL; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00930; NIL; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02314; ABC_MetN; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51264; METN; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UJA1.
DR   SWISS-2DPAGE; B7UJA1.
KW   Amino-acid transport {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|SAAS:SAAS00433007};
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01719, ECO:0000256|PROSITE-
KW   ProRule:PRU00434, ECO:0000256|SAAS:SAAS00035635,
KW   ECO:0000313|EMBL:CAS07753.1};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01719};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|SAAS:SAAS00433023};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|SAAS:SAAS00432985};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|SAAS:SAAS00433044};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|PROSITE-ProRule:PRU00434, ECO:0000256|SAAS:SAAS00035551};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01719,
KW   ECO:0000256|SAAS:SAAS00433037}.
FT   DOMAIN        2    241       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   DOMAIN      238    343       METN. {ECO:0000259|PROSITE:PS51264}.
FT   NP_BIND      38     45       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   343 AA;  37802 MW;  D99EF7E7BD904491 CRC64;
     MIKLSNITKV FHQGTRTIQA LNNVSLHVPA GQIYGVIGAS GAGKSTLIRC VNLLERPTEG
     SVLVDGQELT TLSESELTKA RRQIGMIFQH FNLLSSRTVF GNVALPLELD NTPKDEIKRR
     VTELLSLVGL GDKHDSYPSN LSGGQKQRVA IARALASNPK VLLCDEATSA LDPATTRSIL
     ELLKDINRRL GLTILLITHE MDVVKRICDC VAVISNGELI EQDTVSEVFS HPKTPLAQKF
     IQSTLHLDIP EDYQERLQAE PFTDCVPMLR LEFTGQSVDA PLLSETARRF NVNNNIISAQ
     MDYAGGVKFG IMLTEMHGTQ QDTQAAIAWL QEHHVKVEVL GYV
//

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