(data stored in ACNUC30630 zone)

SWISSPROT: B8BNJ9_ORYSI

ID   B8BNJ9_ORYSI            Unreviewed;       391 AA.
AC   B8BNJ9;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   11-DEC-2019, entry version 63.
DE   RecName: Full=tRNA pseudouridine synthase {ECO:0000256|RuleBase:RU003792};
DE            EC=5.4.99.12 {ECO:0000256|RuleBase:RU003792};
GN   ORFNames=OsI_37759 {ECO:0000313|EMBL:EEC68990.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000313|EMBL:EEC68990.1, ECO:0000313|Proteomes:UP000007015};
RN   [1] {ECO:0000313|EMBL:EEC68990.1, ECO:0000313|Proteomes:UP000007015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA;
CC         Xref=Rhea:RHEA:22376, Rhea:RHEA-COMP:10085, Rhea:RHEA-COMP:10087,
CC         ChEBI:CHEBI:65314, ChEBI:CHEBI:65315; EC=5.4.99.12;
CC         Evidence={ECO:0000256|RuleBase:RU003792};
CC   -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC       {ECO:0000256|RuleBase:RU003792}.
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DR   EMBL; CM000137; EEC68990.1; -; Genomic_DNA.
DR   EnsemblPlants; BGIOSGA037127-TA; BGIOSGA037127-PA; BGIOSGA037127.
DR   Gramene; BGIOSGA037127-TA; BGIOSGA037127-PA; BGIOSGA037127.
DR   eggNOG; KOG4393; Eukaryota.
DR   eggNOG; COG0101; LUCA.
DR   HOGENOM; HOG000248674; -.
DR   OMA; FRATGCQ; -.
DR   Proteomes; UP000007015; Chromosome 12.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0106029; F:tRNA pseudouridine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.660; -; 2.
DR   HAMAP; MF_00171; TruA; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR001406; PsdUridine_synth_TruA.
DR   InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR   InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR   PANTHER; PTHR11142; PTHR11142; 1.
DR   Pfam; PF01416; PseudoU_synth_1; 2.
DR   SUPFAM; SSF55120; SSF55120; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8BNJ9.
DR   SWISS-2DPAGE; B8BNJ9.
KW   Isomerase {ECO:0000256|RuleBase:RU003792};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007015};
KW   tRNA processing {ECO:0000256|RuleBase:RU003792}.
FT   DOMAIN          76..186
FT                   /note="PseudoU_synth_1"
FT                   /evidence="ECO:0000259|Pfam:PF01416"
FT   DOMAIN          227..388
FT                   /note="PseudoU_synth_1"
FT                   /evidence="ECO:0000259|Pfam:PF01416"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   391 AA;  42621 MW;  DC463507BF28D6AF CRC64;
     MSAATPDSAA AAKRPIDPSH ADPSPAAKLQ RSSPPDPSPP AEAQGDTTDG GGEVAGVRSG
     EMAGARNPQA QRYLVAVEYV GTRFSGSQQQ LNQRTVVGVL EEAFHKFIGQ PVSIFCSSRT
     DTGVHALSNV CHVDVERISK RKPGEMLPPH EPGVVKRAVN HFLQKNEGDI MVTDVRCVAP
     DFHARYKALE RTYHYRLLSG SEPLSVFEKT SAWHIPEDLN VQAMKKACSI LVGHHDFSSF
     RATGCQANSP MRTLDELSVT EVFPSMFFPS SMERSEMESL DGHLVYSRTS VVESSGKGSD
     ASSTSEQSRF ENGEEFGKRL RHRCFVVTAR ARSFLYHQVR LMVGLLKSVG TGDLTTEDVE
     RILNLKAVTA APPMAPACGL YLANVKYDLS V
//

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