(data stored in ACNUC9543 zone)

SWISSPROT: B8CBV2_THAPS

ID   B8CBV2_THAPS            Unreviewed;       720 AA.
AC   B8CBV2;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   08-MAY-2019, entry version 56.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:EED89385.1};
GN   ORFNames=THAPSDRAFT_42282 {ECO:0000313|EMBL:EED89385.1};
OS   Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC   Eukaryota; Stramenopiles; Bacillariophyta; Coscinodiscophyceae;
OC   Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae;
OC   Thalassiosira.
OX   NCBI_TaxID=35128 {ECO:0000313|Proteomes:UP000001449};
RN   [1] {ECO:0000313|EMBL:EED89385.1, ECO:0000313|Proteomes:UP000001449}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1335 {ECO:0000313|EMBL:EED89385.1,
RC   ECO:0000313|Proteomes:UP000001449};
RX   PubMed=15459382; DOI=10.1126/science.1101156;
RA   Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA   Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M.,
RA   Brzezinski M.A., Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S.,
RA   Detter J.C., Glavina T., Goodstein D., Hadi M.Z., Hellsten U.,
RA   Hildebrand M., Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N.,
RA   Lau W.W., Lane T.W., Larimer F.W., Lippmeier J.C., Lucas S.,
RA   Medina M., Montsant A., Obornik M., Parker M.S., Palenik B.,
RA   Pazour G.J., Richardson P.M., Rynearson T.A., Saito M.A.,
RA   Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A., Wilkerson F.P.,
RA   Rokhsar D.S.;
RT   "The genome of the diatom Thalassiosira pseudonana: ecology,
RT   evolution, and metabolism.";
RL   Science 306:79-86(2004).
RN   [2] {ECO:0000313|EMBL:EED89385.1, ECO:0000313|Proteomes:UP000001449}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1335 {ECO:0000313|EMBL:EED89385.1,
RC   ECO:0000313|Proteomes:UP000001449};
RX   PubMed=18923393; DOI=10.1038/nature07410;
RA   Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA   Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E.,
RA   Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M.,
RA   Katinka M., Mock T., Valentin K., Verret F., Berges J.A., Brownlee C.,
RA   Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A.,
RA   Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M.,
RA   Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y.,
RA   Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E.,
RA   Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M.,
RA   McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C.,
RA   Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N.,
RA   Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H.,
RA   Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A.,
RA   von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S.,
RA   Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA   Grigoriev I.V.;
RT   "The Phaeodactylum genome reveals the evolutionary history of diatom
RT   genomes.";
RL   Nature 456:239-244(2008).
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DR   EMBL; CM000648; EED89385.1; -; Genomic_DNA.
DR   RefSeq; XP_002293649.1; XM_002293613.1.
DR   STRING; 35128.Thaps42282; -.
DR   EnsemblProtists; EED89385; EED89385; THAPSDRAFT_42282.
DR   GeneID; 7450521; -.
DR   KEGG; tps:THAPSDRAFT_42282; -.
DR   eggNOG; KOG0925; Eukaryota.
DR   eggNOG; COG1643; LUCA.
DR   HOGENOM; HOG000175261; -.
DR   InParanoid; B8CBV2; -.
DR   KO; K12820; -.
DR   Proteomes; UP000001449; Chromosome 13.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034459; F:ATP-dependent 3'-5' RNA helicase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
DR   PRODOM; B8CBV2.
DR   SWISS-2DPAGE; B8CBV2.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01176619};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001449};
KW   Helicase {ECO:0000313|EMBL:EED89385.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01176622};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01176608};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001449}.
FT   DOMAIN       65    236       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      258    441       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
SQ   SEQUENCE   720 AA;  80348 MW;  CDC5FC0A22B8C7B5 CRC64;
     MGGTDRKRKL NLSTDETVKQ QKSTLDARQS SSINPWTSQP YSSRYQSILQ TRLKLPVYQF
     QSQLLEAVAS NQIVVVEGET GSGKTTQIPQ FLVEVGYATP GNNCVACTQP RRVAATSIAT
     RVADEMDVTL GGTVGYTIRF EDVSSEETVL KFLTDGMLLR EAMNDPLLSR YSVIVLDEAH
     ERTLATDVLM GLLMEVIPKR TKGSKYGELK VVVMSATLDA AKFQEYFNGA PLLKVPGRTF
     PVEVFYTAEP ERNYVEAAVR TAIQIHKCEG PGDILVFLTG EQEIEQACEE IRGGAMDMGK
     DAPELVVYPL YSSLPPAQQR KIFSAAPGPR VVGGPPGRKV VVSTNIAETS LTIDGIVYVI
     DPGFSKQKVY NPRIRVESLL VSPISRASAR QRSGRAGRTR PGKCFRLYTE QSFHNDLQET
     TYPEILRSKM SNVVLTLKKL GIDDLVHFDF MDPPAPETLM RALEVLNYLG ALDDEGDLTD
     LGRQMAELPL DPQLSKMLIS SPDYNCSEEI VSIVAAMSVP QIFMRPREAA KAADEAKAQF
     VDATSDHITL LNAYAAYEEV PVAERKQWCW DNFINDRSIS SAESVKKQLR GIMTRLDIPL
     LTCRGKNGNY DTNAIRMTLT TAMYMQVAYL QRAGNYLTVK DNQIVYIHPG SSIDGKPQWV
     LFEEFALTSK NYIRTVTTTK GEWLVEMAPH YFDLENFPEC EAKDELVLEY KKMARRMTSK
//

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