(data stored in SCRATCH zone)

SWISSPROT: B8I9G8_METNO

ID   B8I9G8_METNO            Unreviewed;       215 AA.
AC   B8I9G8;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 63.
DE   RecName: Full=Cytochrome c biogenesis ATP-binding export protein CcmA {ECO:0000256|HAMAP-Rule:MF_01707};
DE            EC=3.6.3.41 {ECO:0000256|HAMAP-Rule:MF_01707};
DE   AltName: Full=Heme exporter protein A {ECO:0000256|HAMAP-Rule:MF_01707};
GN   Name=ccmA {ECO:0000256|HAMAP-Rule:MF_01707};
GN   OrderedLocusNames=Mnod_0175 {ECO:0000313|EMBL:ACL55221.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55221.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55221.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex CcmAB involved in
CC       the biogenesis of c-type cytochromes; once thought to export heme,
CC       this seems not to be the case, but its exact role is uncertain.
CC       Responsible for energy coupling to the transport system.
CC       {ECO:0000256|HAMAP-Rule:MF_01707, ECO:0000256|SAAS:SAAS00381217}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O + heme(In) = ADP + phosphate +
CC       heme(Out). {ECO:0000256|HAMAP-Rule:MF_01707,
CC       ECO:0000256|SAAS:SAAS00381233}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (CcmA) and two transmembrane proteins (CcmB). {ECO:0000256|HAMAP-
CC       Rule:MF_01707}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01707}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01707}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. CcmA
CC       exporter (TC 3.A.1.107) family. {ECO:0000256|HAMAP-Rule:MF_01707,
CC       ECO:0000256|SAAS:SAAS00569443}.
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DR   EMBL; CP001349; ACL55221.1; -; Genomic_DNA.
DR   RefSeq; WP_015926934.1; NC_011894.1.
DR   ProteinModelPortal; B8I9G8; -.
DR   STRING; 460265.Mnod_0175; -.
DR   EnsemblBacteria; ACL55221; ACL55221; Mnod_0175.
DR   KEGG; mno:Mnod_0175; -.
DR   eggNOG; ENOG4107EV4; Bacteria.
DR   eggNOG; COG4133; LUCA.
DR   KO; K02193; -.
DR   OMA; MVVLTTH; -.
DR   OrthoDB; POG091H0404; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015439; F:heme-transporting ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0103115; F:protoheme IX ABC transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR005895; ABC_transptr_haem_export_CcmA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01189; ccmA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51243; CCMA; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8I9G8.
DR   SWISS-2DPAGE; B8I9G8.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01707, ECO:0000256|PROSITE-
KW   ProRule:PRU00434, ECO:0000256|SAAS:SAAS00083062};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01707};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|SAAS:SAAS00458389};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Cytochrome c-type biogenesis {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|SAAS:SAAS00083055};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|SAAS:SAAS00083065};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|SAAS:SAAS00083058};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|PROSITE-ProRule:PRU00434, ECO:0000256|SAAS:SAAS00083060};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01707,
KW   ECO:0000256|SAAS:SAAS00083064}.
FT   DOMAIN        3    215       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      35     42       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   215 AA;  22493 MW;  297337401B5A373E CRC64;
     MRLIAKGLAC RRSGRRIFSG LSFTLDPGEA LIVTGRNGAG KSSLLAILSG RLSPEAGSLR
     AEDVGERTIP ECLHGVGHRD GLKSALTAEE NLAFARDLLG AATLAPREAL ARMGLAHAAG
     LPVAYLSAGQ RRRVALARLL VCRRPLWLLD EPTAALDAAS QAVLAGLMRD HLAEGGLVVA
     ATHQALGLTT ARELSIEAFR PAAAAHTDPF AETAR
//

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