(data stored in SCRATCH zone)

SWISSPROT: B8I9J9_METNO

ID   B8I9J9_METNO            Unreviewed;       465 AA.
AC   B8I9J9;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=NAD(P) transhydrogenase subunit beta {ECO:0000256|PIRNR:PIRNR000204};
DE            EC=1.6.1.2 {ECO:0000256|PIRNR:PIRNR000204};
DE   AltName: Full=Nicotinamide nucleotide transhydrogenase subunit beta {ECO:0000256|PIRNR:PIRNR000204};
GN   OrderedLocusNames=Mnod_0207 {ECO:0000313|EMBL:ACL55252.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55252.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55252.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The transhydrogenation between NADH and NADP is coupled
CC       to respiration and ATP hydrolysis and functions as a proton pump
CC       across the membrane. {ECO:0000256|PIRNR:PIRNR000204}.
CC   -!- CATALYTIC ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH.
CC       {ECO:0000256|PIRNR:PIRNR000204}.
CC   -!- SIMILARITY: Belongs to the PNT beta subunit family.
CC       {ECO:0000256|PIRNR:PIRNR000204}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001349; ACL55252.1; -; Genomic_DNA.
DR   RefSeq; WP_015926965.1; NC_011894.1.
DR   ProteinModelPortal; B8I9J9; -.
DR   STRING; 460265.Mnod_0207; -.
DR   EnsemblBacteria; ACL55252; ACL55252; Mnod_0207.
DR   KEGG; mno:Mnod_0207; -.
DR   eggNOG; ENOG4105C15; Bacteria.
DR   eggNOG; COG1282; LUCA.
DR   HOGENOM; HOG000243958; -.
DR   KO; K00325; -.
DR   OMA; KRGMSAG; -.
DR   OrthoDB; POG091H03IN; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008750; F:NAD(P)+ transhydrogenase (AB-specific) activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.1220; -; 1.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   InterPro; IPR012136; NADH_DH_b.
DR   InterPro; IPR034300; PNTB-like.
DR   Pfam; PF02233; PNTB; 1.
DR   PIRSF; PIRSF000204; PNTB; 1.
DR   SUPFAM; SSF52467; SSF52467; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8I9J9.
DR   SWISS-2DPAGE; B8I9J9.
KW   Cell inner membrane {ECO:0000256|PIRNR:PIRNR000204};
KW   Cell membrane {ECO:0000256|PIRNR:PIRNR000204};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Membrane {ECO:0000256|PIRNR:PIRNR000204, ECO:0000256|SAM:Phobius};
KW   NAD {ECO:0000256|PIRNR:PIRNR000204};
KW   NADP {ECO:0000256|PIRNR:PIRNR000204};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000204,
KW   ECO:0000313|EMBL:ACL55252.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     23       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     35     53       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     59     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     90    111       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    131    152       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    168    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    192    211       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        7    463       PNTB. {ECO:0000259|Pfam:PF02233}.
SQ   SEQUENCE   465 AA;  48522 MW;  B8EBE6C852E87AFB CRC64;
     MSENISSLLY IVAGVLFIMA LRGLSHPTTS RQGNLYGMVG MGIAILTTLV GHAPAGAGAW
     LLVLLGLGIG GGVGAVIARR VPMTAMPQLV AAFHSLVGLA AVAVAAGALY APHAFGILEG
     GHIHKQSLFE MGLGVAIGAI TFTGSVIAFL KLDGRMSGKP IMLPQRHLIN ILLGVLLVVL
     LATFIANESK VLFWLIVLLS FALGGLLIIP IGGADMPVVV SMLNSYSGWA AAGIGFTLGN
     LALIITGSLV GSSGAILSYI MCHAMNRSFI SVILGGFGGE SAVAAGGQVE ARPVKQGSAD
     DAAFIMKNAE KVIIVPGYGM AVAQAQHSLR EMADQLKKEG VEVKYAIHPV AGRMPGHMNV
     LLAEANVPYD EVFELEDING EFPQADVAFV IGANDVTNPA AKTDPQSPIF GMPILDVEKA
     KTVLFVKRGM GSGYAGVENE VFFRDNTMML FGDAKKVVDE IVKSF
//

If you have problems or comments...

PBIL Back to PBIL home page