(data stored in SCRATCH zone)

SWISSPROT: B8ICF5_METNO

ID   B8ICF5_METNO            Unreviewed;       374 AA.
AC   B8ICF5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   30-AUG-2017, entry version 72.
DE   SubName: Full=Transcriptional regulator, AraC family {ECO:0000313|EMBL:ACL55543.1};
GN   OrderedLocusNames=Mnod_0501 {ECO:0000313|EMBL:ACL55543.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55543.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55543.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000409-3};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR000409-
CC       3};
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DR   EMBL; CP001349; ACL55543.1; -; Genomic_DNA.
DR   RefSeq; WP_015927253.1; NC_011894.1.
DR   ProteinModelPortal; B8ICF5; -.
DR   STRING; 460265.Mnod_0501; -.
DR   EnsemblBacteria; ACL55543; ACL55543; Mnod_0501.
DR   KEGG; mno:Mnod_0501; -.
DR   eggNOG; ENOG4105K85; Bacteria.
DR   eggNOG; COG0350; LUCA.
DR   eggNOG; COG2169; LUCA.
DR   HOGENOM; HOG000244139; -.
DR   KO; K10778; -.
DR   OMA; KTTGVYC; -.
DR   OrthoDB; POG091H02CY; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0003908; F:methylated-DNA-[protein]-cysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06445; ATase; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.10.10; -; 1.
DR   InterPro; IPR035451; Ada-like_domain.
DR   InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR   InterPro; IPR016221; Bifunct_regulatory_prot_Ada.
DR   InterPro; IPR009057; Homeobox-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   InterPro; IPR001497; MethylDNA_cys_MeTrfase_AS.
DR   InterPro; IPR014048; MethylDNA_cys_MeTrfase_DNA-bd.
DR   InterPro; IPR008332; MethylG_MeTrfase_N.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF02805; Ada_Zn_binding; 1.
DR   Pfam; PF01035; DNA_binding_1; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   PIRSF; PIRSF000409; Ada; 1.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF46767; SSF46767; 1.
DR   SUPFAM; SSF53155; SSF53155; 1.
DR   SUPFAM; SSF57884; SSF57884; 1.
DR   TIGRFAMs; TIGR00589; ogt; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 2.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR   PROSITE; PS00374; MGMT; 1.
PE   4: Predicted;
DR   PRODOM; B8ICF5.
DR   SWISS-2DPAGE; B8ICF5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00593,
KW   ECO:0000256|SAAS:SAAS00048696};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000409-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transcription {ECO:0000256|PROSITE-ProRule:PRU00593};
KW   Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00593};
KW   Zinc {ECO:0000256|PIRSR:PIRSR000409-3}.
FT   DOMAIN       94    191       HTH araC/xylS-type DNA-binding.
FT                                {ECO:0000259|PROSITE:PS01124}.
FT   DNA_BIND    110    131       H-T-H motif. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00593}.
FT   DNA_BIND    158    181       H-T-H motif. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00593}.
FT   ACT_SITE     44     44       Nucleophile; methyl group acceptor from
FT                                phosphotriester. {ECO:0000256|PIRSR:
FT                                PIRSR000409-1}.
FT   ACT_SITE    330    330       Nucleophile; methyl group acceptor from
FT                                either O6-methylguanine or O4-
FT                                methylthymine. {ECO:0000256|PIRSR:
FT                                PIRSR000409-1}.
FT   METAL        44     44       Zinc. {ECO:0000256|PIRSR:PIRSR000409-3}.
FT   METAL        48     48       Zinc. {ECO:0000256|PIRSR:PIRSR000409-3}.
FT   METAL        75     75       Zinc. {ECO:0000256|PIRSR:PIRSR000409-3}.
FT   METAL        78     78       Zinc. {ECO:0000256|PIRSR:PIRSR000409-3}.
SQ   SEQUENCE   374 AA;  39865 MW;  29D7078682D0B3CA CRC64;
     MKLPDPDPPV MRPDEAACRA ALARRDPAAD GTFVYAVRTT GVYCRPSCPA RTARPENVSF
     YATCAEAEAA GFRPCRRCRP NEPGLAARQA EAVARACRLI EEAETPPSLD ALSRTEGLSP
     YHFHRIFKRI TGVTPKAYAA ARRAARLESG LLRDAGTVTE AIFEAGYGTS SRFYAAAAAR
     LGMTPTAYRR GGAGTAIRFA VAACSLGAVL VAATQKGVCA IMLGDDPEAL VRDLQDRFPR
     AELTGGDAEF ETVVAQVVGL VEAPGTARFD LPLDINGTAF QQRVWQALRA IPPGRTATYT
     QIAQAIGEPK AVRAVAQACG ANPLAVAIPC HRVVRHDGAL SGYRWGVARK RDLLARESTT
     TRDEAQGDLA LDGK
//

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