(data stored in SCRATCH zone)

SWISSPROT: B8IU93_METNO

ID   B8IU93_METNO            Unreviewed;       647 AA.
AC   B8IU93;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 55.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ACL55138.1};
GN   OrderedLocusNames=Mnod_0089 {ECO:0000313|EMBL:ACL55138.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55138.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55138.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001349; ACL55138.1; -; Genomic_DNA.
DR   ProteinModelPortal; B8IU93; -.
DR   STRING; 460265.Mnod_0089; -.
DR   EnsemblBacteria; ACL55138; ACL55138; Mnod_0089.
DR   KEGG; mno:Mnod_0089; -.
DR   eggNOG; ENOG4108059; Bacteria.
DR   eggNOG; COG2114; LUCA.
DR   eggNOG; COG5616; LUCA.
DR   HOGENOM; HOG000012562; -.
DR   OMA; HETTTHP; -.
DR   OrthoDB; POG091H0Y72; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 3.
DR   Gene3D; 3.30.70.1230; -; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50293; TPR_REGION; 3.
PE   4: Predicted;
DR   PRODOM; B8IU93.
DR   SWISS-2DPAGE; B8IU93.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    203    224       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12    128       Guanylate cyclase. {ECO:0000259|PROSITE:
FT                                PS50125}.
FT   DOMAIN      414    430       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   DOMAIN      475    542       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   DOMAIN      579    612       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
SQ   SEQUENCE   647 AA;  70974 MW;  B6709FBF389F6890 CRC64;
     MDQTIADRRL VTILVADVVG YSRLIGADET GTLRRLKALR RDVIGPSIAA SKGRIIKTVG
     DGFIAEFGSA VRAVNCAISI QQGLARHEAG IAEDRALRLR IGINLGDVVV EPDGDLYGDG
     VNVAARLEPL SEAGGICLSR SVYDQVRDKL RYPFQDRGKL ELKNIARPVG VFSLPASAIA
     DLTDTDEQVP EPVKTSNRKP WKATAVGAGF LTLLAAGGLG WWSWTASKAP APNQTIAAKL
     AGETREAPRL SIVVLPFSNL SNDPEQDYFA DSITEDLTTD LSHLAGSFVI ARNTAFTYKN
     KPVDVKQIGR ELGVRYVLEG SVRRTGEKVV LNSQLISAET GAHIWSDRFD GDRSRLGDLQ
     VEFVARLARS LDVQLTEAES LRSFRERPVN LDASDLAMRG WASLNKQRSV ANNNEAVQYF
     SQALKLDPNL PRAVLGLSRA LMNKVINRWS EDIQADIEGS DGLITKYIEK FPSDAAALVV
     KGDVFRSNKH FDAALAMYDA AIVANRNFAA AYALKGHVSL LSGKAYAAIP SEIEAIRISP
     RDPLVNVWYY FVCHAHTHMA QWEEAIAWCN KCVAISPFWQ AYIDLAAAYA WTGRAYEAKA
     AVSELLKLMP GYTVKKWATA GWSNHSRFLE EYQLIVEGLR KAGLQEE
//

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