(data stored in SCRATCH zone)

SWISSPROT: B8IUB2_METNO

ID   B8IUB2_METNO            Unreviewed;       411 AA.
AC   B8IUB2;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   05-JUL-2017, entry version 58.
DE   RecName: Full=Aspartokinase {ECO:0000256|RuleBase:RU003448};
DE            EC=2.7.2.4 {ECO:0000256|RuleBase:RU003448};
GN   OrderedLocusNames=Mnod_0110 {ECO:0000313|EMBL:ACL55157.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55157.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55157.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + L-aspartate = ADP + 4-phospho-L-
CC       aspartate. {ECO:0000256|RuleBase:RU003448}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de
CC       novo pathway; L-homoserine from L-aspartate: step 1/3.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-
CC       threonine from L-aspartate: step 1/5.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- SIMILARITY: Belongs to the aspartokinase family.
CC       {ECO:0000256|RuleBase:RU003448}.
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DR   EMBL; CP001349; ACL55157.1; -; Genomic_DNA.
DR   RefSeq; WP_012634396.1; NC_011894.1.
DR   ProteinModelPortal; B8IUB2; -.
DR   STRING; 460265.Mnod_0110; -.
DR   EnsemblBacteria; ACL55157; ACL55157; Mnod_0110.
DR   KEGG; mno:Mnod_0110; -.
DR   eggNOG; ENOG4105CFH; Bacteria.
DR   eggNOG; COG0527; LUCA.
DR   HOGENOM; HOG000293093; -.
DR   KO; K00928; -.
DR   OMA; INIMMIS; -.
DR   OrthoDB; POG091H0223; -.
DR   UniPathway; UPA00034; UER00015.
DR   UniPathway; UPA00050; UER00461.
DR   UniPathway; UPA00051; UER00462.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0004072; F:aspartate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR005260; Asp_kin_monofn.
DR   InterPro; IPR001341; Asp_kinase_dom.
DR   InterPro; IPR018042; Aspartate_kinase_CS.
DR   InterPro; IPR027795; GATS-like_ACT_dom.
DR   Pfam; PF00696; AA_kinase; 1.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF13840; ACT_7; 1.
DR   PIRSF; PIRSF000726; Asp_kin; 2.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00656; asp_kin_monofn; 1.
DR   TIGRFAMs; TIGR00657; asp_kinases; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00324; ASPARTOKINASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8IUB2.
DR   SWISS-2DPAGE; B8IUB2.
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU004249};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Kinase {ECO:0000256|RuleBase:RU003448, ECO:0000313|EMBL:ACL55157.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transferase {ECO:0000256|RuleBase:RU003448,
KW   ECO:0000313|EMBL:ACL55157.1}.
FT   DOMAIN      269    353       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   411 AA;  44029 MW;  81F2D1952345ED23 CRC64;
     MPRLVMKFGG TSVATVDRIR NVARHVAREV RAGYEVAVVV SAMAGKTNEL VAWCKDASPL
     YAQSEYDAVV ASGEQVTSGL LAIVLAEMGI KARSWQGWQI PIETSDQHGS ARIARIDGSR
     LDAGFRHGEV AVIAGFQGIH AETGRLTTLG RGGSDTSAVA VAAAIGAERC DIYTDVDGVY
     TTDPRVVPKA RRLERVAFEE MLEMASLGAK VLQVRSVELA MVHRVPTTVR SSFDDPDDAR
     PGTLICDEDD IVEQQIITGI AFSKDEAQIT LRRVKDRPGV AAAIFGPLAD ANINVDMIIQ
     VVSGDGVTTD MTFTVPASDY ERARTILDAQ SGKVEFERIE GATDVVKISA IGVGMRSHAG
     VAAKAFRALA DKGINIRAIT TSEIKFSVLI DAAYTELAVR TLHSLYGLDR A
//

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