(data stored in ACNUC11299 zone)

SWISSPROT: B9WN64_CANDC

ID   B9WN64_CANDC            Unreviewed;      1735 AA.
AC   B9WN64;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 50.
DE   RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE            EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN   OrderedLocusNames=Cd36_35480 {ECO:0000313|CGD:CAL0000170322};
GN   ORFNames=CD36_35480 {ECO:0000313|EMBL:CAX40531.1};
OS   Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF
OS   3949 / NRRL Y-17841) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae;
OC   Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=573826 {ECO:0000313|EMBL:CAX40531.1, ECO:0000313|Proteomes:UP000002605};
RN   [1] {ECO:0000313|EMBL:CAX40531.1, ECO:0000313|Proteomes:UP000002605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841
RC   {ECO:0000313|Proteomes:UP000002605};
RX   PubMed=19745113; DOI=10.1101/gr.097501.109;
RA   Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D.,
RA   Harris D., Aslett M., Barrell J.F., Butler G., Citiulo F.,
RA   Coleman D.C., de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J.,
RA   Munro C.A., Pain A., Poulter R.T., Rajandream M.A., Renauld H.,
RA   Spiering M.J., Tivey A., Gow N.A.R., Barrell B., Sullivan D.J.,
RA   Berriman M.;
RT   "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT   Candida albicans.";
RL   Genome Res. 19:2231-2244(2009).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000256|RuleBase:RU004279}.
CC   -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
CC       + RNA(n+1). {ECO:0000256|RuleBase:RU004279}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000256|RuleBase:RU004279}.
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DR   EMBL; FM992695; CAX40531.1; -; Genomic_DNA.
DR   RefSeq; XP_002422523.1; XM_002422478.1.
DR   STRING; 573826.XP_002422523.1; -.
DR   EnsemblFungi; CAX40531; CAX40531; CD36_35480.
DR   GeneID; 8049648; -.
DR   KEGG; cdu:CD36_35480; -.
DR   CGD; CAL0000170322; Cd36_35480.
DR   eggNOG; KOG0260; Eukaryota.
DR   eggNOG; COG0086; LUCA.
DR   HOGENOM; HOG000222975; -.
DR   KO; K03006; -.
DR   OrthoDB; EOG092C01XQ; -.
DR   Proteomes; UP000002605; Chromosome R.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:EnsemblFungi.
DR   GO; GO:0003677; F:DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR007075; RNA_pol_Rpb1_6.
DR   InterPro; IPR007073; RNA_pol_Rpb1_7.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR   Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR   Pfam; PF05001; RNA_pol_Rpb1_R; 18.
DR   SMART; SM00663; RPOLA_N; 1.
DR   PROSITE; PS00115; RNA_POL_II_REPEAT; 11.
PE   3: Inferred from homology;
DR   PRODOM; B9WN64.
DR   SWISS-2DPAGE; B9WN64.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002605};
KW   DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:CAX40531.1};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:CAX40531.1};
KW   Transcription {ECO:0000256|RuleBase:RU004279};
KW   Transferase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:CAX40531.1}.
FT   DOMAIN      232    535       RPOLA_N. {ECO:0000259|SMART:SM00663}.
SQ   SEQUENCE   1735 AA;  192752 MW;  6C2B27497FD7DEE2 CRC64;
     MSRQFPYSSA PLRSVKEVQF GLLSPEEVRA ISVAKIEYPE TMDQTTKRPR EGGLNDPRLG
     SIDRNFRCQT CGEDMAECPG HFGHIELAKP VFHIGFIAKI KKACESVCMH CGKLLLDETN
     PAMAQAIKIR DPKKRFNAVW SLCKSKMVCE TDNNEDEMTD QPSRGGCGHP QPTIRRDGLK
     LWGTWKQNKN YDDNEQPERR LLTPSEILNV FKHISPEDCH KMGFNEDYAR PEWMLITVLP
     VPPPPVRPSI AFNETARGED DLTFKLADII KANINVQRLE TDGSPQHVIS EFEALLQFHV
     ATYMDNDIAG QPQALQKTGR PIKSIRARLK GKEGRLRGNL MGKRVDFSAR TVISGDPNLD
     LDQVGVPISI AKTLTYPEIV TPYNIHKLTE LVRNGPNEHP GAKYVIRDTG DRIDLRYNKR
     AGDIALQYGW KVERHLMDDD PVLFNRQPSL HKMSMMAHRV RVMPYSTFRL NLSVTSPYNA
     DFDGDEMNLH VPQSPETRAE LSQICAVPLQ IVSPQSNKPV MGIVQDTLCG IRKMTLRDIF
     IEYDQVMNMC YWIPNWDGVI PPPAVVKPKP LWTGKQLLSL AIPKGIHLQR FDGGRDLLSP
     KDTGMLIVDG EIMFGVVDKK TVGATGGGLI HTVMREKGPK VCAELFSSIQ KVVNYWLLHN
     GFSIGIGDTI ADAQTMRDVT KTIQEAKQKV QEIIIDAQHN KLEPEPGMTL RESFEHNVSR
     VLNQARDTAG RSAEMSLKDL NNVKQMVTSG SKGSFINISQ MSACVGQQIV EGKRIPFGFG
     DRSLPHFTKD DYSPESKGFV ENSYLRGLTP QEFFFHAMAG REGLIDTAVK TAETGYIQRR
     LVKALEDIMV HYDGTTRNSL GDIIQFIYGE DGIDGTQVEK QSVDTIPGSD ESFERRYRID
     ILDTKNMISE SLIESGKEIR GDVQLQKILD EEYNQLLKDR KYLREVCFPN GDFSWPLPVN
     LRRIIQNAQQ IFHNGRYRAS DLRLEEIIFG VRELCKKLLV VRGDTPLVKE AQENATLLFQ
     CLLRSRLAAR RVIEEFKLNR VSFEWVLGEI ETQFQKSIVH PGEMVGVVAA QSIGEPATQM
     TLNTFHYAGV SSKNVTLGVP RLKEILNVAK NIKTPAMTVY LDPEVASDIE KAKIVQSAIE
     HTTLKNVTSS AEIYYDPDPR TTVIEDDYDT VEAYFAIPDQ KVEETIDKQS PWLLRLELDR
     AKMLDKQLTM AQVAEKISQN FGEDLFVIWS DDTADKLIIR CRVVRDPKSL DEDADAEEDQ
     ILKRIEAHML ESISLRGIPG ITRVFMMQHK VSHPDETGEF KQGKEWVLET DGVNLADVMA
     VPGVDSARTY SNDFIEVLSV LGIEATRSSL YKEILNVIAF DGSYVNYRHM ALLVDVMTSR
     GHLMAITRHG INRSDTGALM RCSFEETVEI LLDAAAAAEL DDCKGISENV MLGQMAPLGT
     GSFDLMIDER MLQQAPSSIA METIADDGGA TPYKEYESAR DENIEIDAGA GFSPIHTAQV
     NEGIVGGLTS YGGQPTSPAA TSPFSFGYNT ATSPGYASPG YGYSPTSPSY SPTSPSYSPT
     SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP SYSPTSPSYS PTSPSYSPTS PSYSPTSPSY
     SPTSPGYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP QYSPTSPSYS PTSPQYSPTS
     PSYSPTSPQY SPTSPSYSPT SPQYSPTSPQ YSPTSPRYSP GSPGYEPKSP KKDGK
//

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