(data stored in ACNUC7421 zone)

SWISSPROT: YDGK_BACSU

ID   YDGK_BACSU              Reviewed;         402 AA.
AC   P96709; Q797F0; Q79EN3;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   11-DEC-2019, entry version 121.
DE   RecName: Full=Uncharacterized MFS-type transporter YdgK;
GN   Name=ydgK; OrderedLocusNames=BSU05680;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT   "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT   subtilis genome.";
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 116-402.
RC   STRAIN=168 / JH642;
RX   PubMed=9202461; DOI=10.1099/00221287-143-6-1861;
RA   Sadaie Y., Yata K., Fujita M., Sagai H., Itaya M., Kasahara Y.,
RA   Ogasawara N.;
RT   "Nucleotide sequence and analysis of the phoB-rrnE-groESL region of the
RT   Bacillus subtilis chromosome.";
RL   Microbiology 143:1861-1866(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Bcr/CmlA
CC       family. {ECO:0000305}.
DR   EMBL; AB001488; BAA19401.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12387.1; -; Genomic_DNA.
DR   EMBL; D88802; BAA19692.1; -; Genomic_DNA.
DR   PIR; E69783; E69783.
DR   RefSeq; NP_388449.1; NC_000964.3.
DR   RefSeq; WP_003234132.1; NZ_JNCM01000031.1.
DR   STRING; 224308.BSU05680; -.
DR   PaxDb; P96709; -.
DR   PRIDE; P96709; -.
DR   EnsemblBacteria; CAB12387; CAB12387; BSU05680.
DR   GeneID; 938060; -.
DR   KEGG; bsu:BSU05680; -.
DR   PATRIC; fig|224308.179.peg.611; -.
DR   eggNOG; ENOG4105C2C; Bacteria.
DR   eggNOG; ENOG410XNNX; LUCA.
DR   HOGENOM; HOG000143170; -.
DR   InParanoid; P96709; -.
DR   KO; K07552; -.
DR   OMA; MLARAMI; -.
DR   PhylomeDB; P96709; -.
DR   BioCyc; BSUB:BSU05680-MONOMER; -.
DR   PRO; PR:P96709; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006855; P:drug transmembrane transport; IBA:GO_Central.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   InterPro; IPR004812; Efflux_drug-R_Bcr/CmlA.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00710; efflux_Bcr_CflA; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; P96709.
DR   SWISS-2DPAGE; P96709.
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..402
FT                   /note="Uncharacterized MFS-type transporter YdgK"
FT                   /id="PRO_0000359524"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   402 AA;  42681 MW;  60EA33A1CA772DF3 CRC64;
     MLHNPTGKER LALAFLLGML AILGPLNIDM YLPSFPEIAK DLSASASLVQ LSLTACLVGL
     TIGQLIVGPV SDAQGRRKPL LICIFLFALS SLFCALSPNI TTLVAARFLQ GFTASAGLVL
     SRAIVRDVFT GRELSKFFSL LMVITAVAPM VAPMTGGAIL LLPFATWHTI FHVLMIIGFL
     LVLLIALRLK ETLPLEKRIP SSIGTSVKTM GSLLKDRSFM GYALTVGFIH GGSFAYVSGT
     PFVYQDIYGV SPQVFSILFG INGLAIISGS FIIGRFGGII HEKSLLRIAV ITAMIATAVL
     LTMTMIHGPL ATLVISIFIY MITIGMVLTS TFTLAMEKQG HRAGSASALL GMLPLLLGSI
     VSPLVGINET TAVPMGAIMF VTAVIGSLAF FGLTKERVGQ NS
//

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