(data stored in ACNUC7421 zone)

SWISSPROT: FIXC_ECO57

ID   FIXC_ECO57              Reviewed;         428 AA.
AC   Q7AHT0; Q8XA26;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   05-JUL-2017, entry version 79.
DE   RecName: Full=Protein FixC;
GN   Name=fixC; OrderedLocusNames=Z0049, ECs0046;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Could be part of an electron transfer system required
CC       for anaerobic carnitine reduction. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the ETF-QO/FixC family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54346.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33469.1; -; Genomic_DNA.
DR   PIR; F85485; F85485.
DR   PIR; F90634; F90634.
DR   RefSeq; NP_308073.1; NC_002695.1.
DR   RefSeq; WP_001287748.1; NZ_MWVM01000003.1.
DR   ProteinModelPortal; Q7AHT0; -.
DR   SMR; Q7AHT0; -.
DR   STRING; 155864.Z0049; -.
DR   PRIDE; Q7AHT0; -.
DR   EnsemblBacteria; AAG54346; AAG54346; Z0049.
DR   EnsemblBacteria; BAB33469; BAB33469; BAB33469.
DR   GeneID; 913445; -.
DR   KEGG; ece:Z0049; -.
DR   KEGG; ecs:ECs0046; -.
DR   PATRIC; fig|386585.9.peg.145; -.
DR   eggNOG; ENOG4105DWH; Bacteria.
DR   eggNOG; COG0644; LUCA.
DR   HOGENOM; HOG000018936; -.
DR   KO; K00313; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   SUPFAM; SSF51905; SSF51905; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q7AHT0.
DR   SWISS-2DPAGE; Q7AHT0.
KW   Complete proteome; Electron transport; FAD; Flavoprotein;
KW   Oxidoreductase; Transport.
FT   CHAIN         1    428       Protein FixC.
FT                                /FTId=PRO_0000200692.
FT   NP_BIND      12     28       FAD or NAD or NADP. {ECO:0000255}.
SQ   SEQUENCE   428 AA;  45716 MW;  64B034F30D61DCF1 CRC64;
     MSEDIFDAII VGAGLAGSVA ALVLAREGAQ VLVIERGNSA GAKNVTGGRL YAHSLEHIIP
     GFAESAPVER LITHEKLAFM TEKSAMTMDY CNGDETSPSQ RSYSVLRSKF DAWLMEQAEE
     AGAQLITGIR VDNLVQRDGK VVGVEADGDV IEAKTVILAD GVNSILAEKL GMAKRVKPTN
     VAVGVKELIE LPKSVIEDRF QLQGNQGAAC LFAGSPTDGL MGGGFLYTNE NTLSLGLVCG
     LHHLHDAKKS VPQMLEDFKQ HPAVAPLIAG GKLVEYSAHV VPEAGINMLP ELVGDGVLIA
     GDAAGMCMNL GFTIRGMDLA IAAGEAAAKT VLSAMKSDDF SKQKLAEYRQ HLESGPLRDM
     RMYQKLPAFL DNPRMFSGYP ELAVGVARDL FTIDGSAPEL MRKKILRHGK KVGFINLIKD
     GMKGVTVL
//

If you have problems or comments...

PBIL Back to PBIL home page