(data stored in ACNUC7421 zone)

SWISSPROT: THIQ_ECO57

ID   THIQ_ECO57              Reviewed;         232 AA.
AC   Q8XA06; Q7AHS0;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 111.
DE   RecName: Full=Thiamine import ATP-binding protein ThiQ {ECO:0000255|HAMAP-Rule:MF_01723};
DE            EC=3.6.3.- {ECO:0000255|HAMAP-Rule:MF_01723};
GN   Name=thiQ {ECO:0000255|HAMAP-Rule:MF_01723};
GN   OrderedLocusNames=Z0075, ECs0070;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Part of the ABC transporter complex ThiBPQ involved in
CC       thiamine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01723}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (ThiQ), two transmembrane proteins (ThiP) and a solute-binding
CC       protein (ThiB). {ECO:0000255|HAMAP-Rule:MF_01723}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01723}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01723}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Thiamine
CC       importer (TC 3.A.1.19.1) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01723}.
DR   EMBL; AE005174; AAG54370.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33493.1; -; Genomic_DNA.
DR   PIR; F85488; F85488.
DR   PIR; F90637; F90637.
DR   RefSeq; NP_308097.1; NC_002695.1.
DR   RefSeq; WP_000916267.1; NZ_MWVM01000003.1.
DR   ProteinModelPortal; Q8XA06; -.
DR   SMR; Q8XA06; -.
DR   STRING; 155864.Z0075; -.
DR   EnsemblBacteria; AAG54370; AAG54370; Z0075.
DR   EnsemblBacteria; BAB33493; BAB33493; BAB33493.
DR   GeneID; 913478; -.
DR   KEGG; ece:Z0075; -.
DR   KEGG; ecs:ECs0070; -.
DR   PATRIC; fig|386585.9.peg.170; -.
DR   eggNOG; ENOG4107T0D; Bacteria.
DR   eggNOG; COG3840; LUCA.
DR   KO; K02062; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005968; Thiamine_ABC_ThiQ.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01277; thiQ; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51288; THIQ; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XA06.
DR   SWISS-2DPAGE; Q8XA06.
KW   ATP-binding; Cell inner membrane; Cell membrane; Complete proteome;
KW   Hydrolase; Membrane; Nucleotide-binding; Transport.
FT   CHAIN         1    232       Thiamine import ATP-binding protein ThiQ.
FT                                /FTId=PRO_0000274439.
FT   DOMAIN        2    230       ABC transporter. {ECO:0000255|HAMAP-
FT                                Rule:MF_01723}.
FT   NP_BIND      32     39       ATP. {ECO:0000255|HAMAP-Rule:MF_01723}.
SQ   SEQUENCE   232 AA;  25025 MW;  C4C462B8072655F7 CRC64;
     MLKLTDITWL YHHLPMRFSL TVERGEQVAI LGPSGAGKST LLNLIAGFLT PASGALTIDG
     VDHTTTPPSR RPVSMLFQEN NLFSHLTVAQ NIGLGLNPGL KLNAVQQEKM HAIARQMGID
     NLMARLPGEL SGGQRQRVAL ARCLVREQPI LLLDEPFSAL DPALRQEMLT LVSTSCQQQK
     MTLLMVSHSV EDAARIATRS VVVADGRIAW QGMTNELLSG KASASALLGI TG
//

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