(data stored in ACNUC7421 zone)

SWISSPROT: Q8XA05_ECO57

ID   Q8XA05_ECO57            Unreviewed;       536 AA.
AC   Q8XA05; A0A0H3JD98; Q7AHR9;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   08-MAY-2019, entry version 127.
DE   SubName: Full=Thiamine transport system permease {ECO:0000313|EMBL:BAB33494.1};
GN   Name=thiP {ECO:0000313|EMBL:BAB33494.1};
GN   ORFNames=ECs_0071 {ECO:0000313|EMBL:BAB33494.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|EMBL:BAB33494.1, ECO:0000313|Proteomes:UP000000558};
RN   [1] {ECO:0000313|EMBL:BAB33494.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 /
RC   EHEC {ECO:0000313|Proteomes:UP000000558};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363032}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport
CC       system permease family. {ECO:0000256|RuleBase:RU363032}.
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DR   EMBL; BA000007; BAB33494.1; -; Genomic_DNA.
DR   RefSeq; NP_308098.1; NC_002695.1.
DR   RefSeq; WP_000235663.1; NZ_SDVX01000001.1.
DR   STRING; 155864.EDL933_0069; -.
DR   EnsemblBacteria; AAG54371; AAG54371; Z0076.
DR   EnsemblBacteria; BAB33494; BAB33494; BAB33494.
DR   GeneID; 913479; -.
DR   KEGG; ecs:ECs0071; -.
DR   PATRIC; fig|386585.9.peg.171; -.
DR   eggNOG; ENOG4106SMU; Bacteria.
DR   eggNOG; COG1178; LUCA.
DR   KO; K02063; -.
DR   BioCyc; ECOO157:YABK-MONOMER; -.
DR   Proteomes; UP000000558; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0015888; P:thiamine transport; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 2.
DR   Gene3D; 1.10.3720.10; -; 2.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR005947; ThiP_ABC_transpt.
DR   Pfam; PF00528; BPD_transp_1; 2.
DR   SUPFAM; SSF161098; SSF161098; 2.
DR   TIGRFAMs; TIGR01253; thiP; 1.
DR   PROSITE; PS50928; ABC_TM1; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q8XA05.
DR   SWISS-2DPAGE; Q8XA05.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558};
KW   Membrane {ECO:0000256|RuleBase:RU363032};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000558};
KW   Transmembrane {ECO:0000256|RuleBase:RU363032};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363032};
KW   Transport {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM     12     38       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM     58     78       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM     90    114       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    134    151       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    199    220       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    240    260       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    293    311       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    331    354       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    375    394       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    406    424       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    465    484       Helical. {ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM    504    525       Helical. {ECO:0000256|RuleBase:RU363032}.
SQ   SEQUENCE   536 AA;  59395 MW;  99434A9335A54960 CRC64;
     MATRRQPLIP GWLIPGVSAA TLVVAVALAA FLALWWNAPQ GDWSAVWQDS YLWHVVRFSF
     WQAFLSALLS VVPAIFLARA LYRRRFPGRL ALLRLCAMTL ILPVLVAVFG ILSVYGRQGW
     LASLCQSLGL EWTFSPYGLQ GILLAHVFFN LPMASRLLLQ ALENIPGEQR QLAAQLGMRG
     WHFFRFVEWP WLRRQIPPVT ALIFMLCFAS FATVLSLGGG PQATTIELAI YQALSYDYDP
     ARAAMLALIQ MVCCLGLVLL SQRLSKAIAP GTTLLQGWRD PDDRLHSRIC DTMLIVLALL
     LLLPPLLAVI VDGVNRQLPE VLAQPVLWQA LWTSLRIALA AGVLCVVLTM MLLWSSRELR
     ARQKMLAGQA LEMSGMLILA MPGIVLATGF FLLLNNTIGL PQSADGIVIF TNALMAIPYA
     LKVLENPMRD ITARYSMLCQ SLGIEGWSRL KVVELRALKR PLAQALAFAC VLSIGDFGVV
     ALFGNDDFRT LPFYLYQQIG SYRSQDGAVT ALILLLLCFL LFSVIEKIPG RNVKTD
//

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