(data stored in ACNUC7421 zone)

SWISSPROT: Q8X994_ECO57

ID   Q8X994_ECO57            Unreviewed;       132 AA.
AC   Q8X994; Q7AHQ8;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 125.
DE   SubName: Full=7,8-dihydro-8-oxoguanine-triphosphatase {ECO:0000313|EMBL:BAB33526.1};
DE   SubName: Full=7,8-dihydro-8-oxoguanine-triphosphatase, prefers dGTP, causes AT-GC transversions {ECO:0000313|EMBL:AAG54403.1};
GN   Name=mutT {ECO:0000313|EMBL:AAG54403.1};
GN   OrderedLocusNames=ECs0103 {ECO:0000313|EMBL:BAB33526.1}, Z0109
GN   {ECO:0000313|EMBL:AAG54403.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|Proteomes:UP000002519};
RN   [1] {ECO:0000313|EMBL:BAB33526.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558}, and Sakai
RC   {ECO:0000313|EMBL:BAB33526.1};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2] {ECO:0000313|EMBL:AAG54403.1, ECO:0000313|Proteomes:UP000002519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EDL933 {ECO:0000313|EMBL:AAG54403.1}, and O157:H7 / EDL933 /
RC   ATCC 700927 / EHEC {ECO:0000313|Proteomes:UP000002519};
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G.III., Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC       {ECO:0000256|RuleBase:RU003476}.
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DR   EMBL; AE005174; AAG54403.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33526.1; -; Genomic_DNA.
DR   PIR; G85492; G85492.
DR   PIR; G90641; G90641.
DR   RefSeq; NP_308130.1; NC_002695.1.
DR   RefSeq; WP_000736023.1; NZ_MWVM01000012.1.
DR   STRING; 155864.Z0109; -.
DR   EnsemblBacteria; AAG54403; AAG54403; Z0109.
DR   EnsemblBacteria; BAB33526; BAB33526; BAB33526.
DR   GeneID; 913600; -.
DR   KEGG; ece:Z0109; -.
DR   KEGG; ecs:ECs0103; -.
DR   PATRIC; fig|386585.9.peg.203; -.
DR   eggNOG; ENOG4105M6F; Bacteria.
DR   eggNOG; COG0494; LUCA.
DR   HOGENOM; HOG000261967; -.
DR   KO; K03574; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0008413; F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR003561; Mutator_MutT.
DR   InterPro; IPR020476; Nudix_hydrolase.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   InterPro; IPR015797; NUDIX_hydrolase_dom-like.
DR   Pfam; PF00293; NUDIX; 1.
DR   PRINTS; PR01401; MUTATORMUTT.
DR   PRINTS; PR00502; NUDIXFAMILY.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   TIGRFAMs; TIGR00586; mutt; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8X994.
DR   SWISS-2DPAGE; Q8X994.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558,
KW   ECO:0000313|Proteomes:UP000002519};
KW   Hydrolase {ECO:0000256|RuleBase:RU003476,
KW   ECO:0000256|SAAS:SAAS00636473}.
FT   DOMAIN        1    129       Nudix hydrolase. {ECO:0000259|PROSITE:
FT                                PS51462}.
SQ   SEQUENCE   132 AA;  15162 MW;  D4AB8E66D3CC7763 CRC64;
     MKKLQIAVGI IRNENNEIFI TRRAADAHMA NKLEFPGGKI EMGETPEQAV VRELQEEVGI
     TPQHFSLFEK LEYEFPDRHI TLWFWLVESW EGEPWGKEGQ PGKWMSLVGL NADDFPPANE
     PVIAKLKRVY VG
//

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