(data stored in ACNUC7421 zone)

SWISSPROT: ERPA_ECO57

ID   ERPA_ECO57              Reviewed;         114 AA.
AC   P0ACC5; P37026;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   05-JUL-2017, entry version 76.
DE   RecName: Full=Iron-sulfur cluster insertion protein ErpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN   Name=erpA {ECO:0000255|HAMAP-Rule:MF_01380};
GN   OrderedLocusNames=Z0167, ECs0160;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for insertion of 4Fe-4S clusters for at least
CC       IspG. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- COFACTOR:
CC       Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01380};
CC       Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01380};
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01380}.
CC   -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01380}.
DR   EMBL; AE005174; AAG54460.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33583.1; -; Genomic_DNA.
DR   PIR; H85499; H85499.
DR   PIR; H90648; H90648.
DR   RefSeq; NP_308187.1; NC_002695.1.
DR   RefSeq; WP_001295564.1; NZ_MWVM01000012.1.
DR   ProteinModelPortal; P0ACC5; -.
DR   STRING; 155864.Z0167; -.
DR   PRIDE; P0ACC5; -.
DR   EnsemblBacteria; AAG54460; AAG54460; Z0167.
DR   EnsemblBacteria; BAB33583; BAB33583; BAB33583.
DR   GeneID; 913801; -.
DR   KEGG; ece:Z0167; -.
DR   KEGG; ecs:ECs0160; -.
DR   PATRIC; fig|386585.9.peg.260; -.
DR   eggNOG; ENOG4108YX9; Bacteria.
DR   eggNOG; COG0316; LUCA.
DR   HOGENOM; HOG000228313; -.
DR   KO; K15724; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:InterPro.
DR   Gene3D; 2.60.300.12; -; 1.
DR   HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR016092; FeS_cluster_insertion.
DR   InterPro; IPR017870; FeS_cluster_insertion_CS.
DR   InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR00049; TIGR00049; 1.
DR   PROSITE; PS01152; HESB; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0ACC5.
DR   SWISS-2DPAGE; P0ACC5.
KW   Complete proteome; Iron; Iron-sulfur; Metal-binding.
FT   CHAIN         1    114       Iron-sulfur cluster insertion protein
FT                                ErpA.
FT                                /FTId=PRO_0000076991.
FT   METAL        42     42       Iron-sulfur. {ECO:0000255|HAMAP-
FT                                Rule:MF_01380}.
FT   METAL       106    106       Iron-sulfur. {ECO:0000255|HAMAP-
FT                                Rule:MF_01380}.
FT   METAL       108    108       Iron-sulfur. {ECO:0000255|HAMAP-
FT                                Rule:MF_01380}.
SQ   SEQUENCE   114 AA;  12100 MW;  5A032FB5C3E0D04A CRC64;
     MSDDVALPLE FTDAAANKVK SLIADEDNPN LKLRVYITGG GCSGFQYGFT FDDQVNEGDM
     TIEKQGVGLV VDPMSLQYLV GGSVDYTEGL EGSRFIVTNP NAKSTCGCGS SFSI
//

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