(data stored in ACNUC7421 zone)

SWISSPROT: EFTS_ECO57

ID   EFTS_ECO57              Reviewed;         283 AA.
AC   P0A6P3; P02997;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   05-JUL-2017, entry version 89.
DE   RecName: Full=Elongation factor Ts;
DE            Short=EF-Ts;
GN   Name=tsf; OrderedLocusNames=Z0181, ECs0172;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterotetramer composed of two EF-Ts.EF-Tu dimer
CC       complexes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54472.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33595.1; -; Genomic_DNA.
DR   PIR; D85501; D85501.
DR   PIR; D90650; D90650.
DR   RefSeq; NP_308199.1; NC_002695.1.
DR   RefSeq; WP_000818114.1; NZ_MWVM01000012.1.
DR   ProteinModelPortal; P0A6P3; -.
DR   SMR; P0A6P3; -.
DR   MINT; MINT-1273879; -.
DR   STRING; 155864.Z0181; -.
DR   PRIDE; P0A6P3; -.
DR   EnsemblBacteria; AAG54472; AAG54472; Z0181.
DR   EnsemblBacteria; BAB33595; BAB33595; BAB33595.
DR   GeneID; 913854; -.
DR   KEGG; ece:Z0181; -.
DR   KEGG; ecs:ECs0172; -.
DR   PATRIC; fig|386585.9.peg.274; -.
DR   eggNOG; ENOG4105CU7; Bacteria.
DR   eggNOG; COG0264; LUCA.
DR   HOGENOM; HOG000220986; -.
DR   KO; K02357; -.
DR   EvolutionaryTrace; P0A6P3; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 2.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01126; EF_TS_1; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0A6P3.
DR   SWISS-2DPAGE; P0A6P3.
KW   Complete proteome; Cytoplasm; Elongation factor; Protein biosynthesis.
FT   INIT_MET      1      1       Removed. {ECO:0000250}.
FT   CHAIN         2    283       Elongation factor Ts.
FT                                /FTId=PRO_0000161119.
FT   REGION       80     83       Involved in Mg(2+) ion dislocation from
FT                                EF-Tu.
SQ   SEQUENCE   283 AA;  30423 MW;  0B9D21E928A5051C CRC64;
     MAEITASLVK ELRERTGAGM MDCKKALTEA NGDIELAIEN MRKSGAIKAA KKAGNVAADG
     VIKTKIDGNY GIILEVNCQT DFVAKDAGFQ AFADKVLDAA VAGKITDVEV LKAQFEEERV
     ALVAKIGENI NIRRVAALEG DVLGSYQHGA RIGVLVAAKG ADEELVKHIA MHVAASKPEF
     IKPEDVSAEV VEKEYQVQLD IAMQSGKPKE IAEKMVEGRM KKFTGEVSLT GQPFVMEPSK
     TVGQLLKEHN AEVTGFIRFE VGEGIEKVET DFAAEVAAMS KQS
//

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