(data stored in ACNUC7421 zone)

SWISSPROT: METI_ECO57

ID   METI_ECO57              Reviewed;         217 AA.
AC   Q8X800;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 89.
DE   RecName: Full=D-methionine transport system permease protein MetI;
GN   Name=metI; OrderedLocusNames=Z0210, ECs0200;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system
CC       for D-methionine and the toxic methionine analog alpha-methyl-
CC       methionine. Probably responsible for the translocation of the
CC       substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport
CC       system permease family. CysTW subfamily. {ECO:0000305}.
DR   EMBL; AE005174; AAG54500.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33623.1; -; Genomic_DNA.
DR   PIR; H85504; H85504.
DR   PIR; H90653; H90653.
DR   RefSeq; NP_308227.1; NC_002695.1.
DR   RefSeq; WP_001294606.1; NZ_MWVM01000012.1.
DR   ProteinModelPortal; Q8X800; -.
DR   SMR; Q8X800; -.
DR   STRING; 155864.Z0210; -.
DR   EnsemblBacteria; AAG54500; AAG54500; Z0210.
DR   EnsemblBacteria; BAB33623; BAB33623; BAB33623.
DR   GeneID; 913960; -.
DR   KEGG; ece:Z0210; -.
DR   KEGG; ecs:ECs0200; -.
DR   PATRIC; fig|386585.9.peg.304; -.
DR   eggNOG; ENOG4108UMI; Bacteria.
DR   eggNOG; COG2011; LUCA.
DR   HOGENOM; HOG000222815; -.
DR   KO; K02072; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   CDD; cd06261; TM_PBP2; 1.
DR   InterPro; IPR000515; MetI-like.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8X800.
DR   SWISS-2DPAGE; Q8X800.
KW   Amino-acid transport; Cell inner membrane; Cell membrane;
KW   Complete proteome; Membrane; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    217       D-methionine transport system permease
FT                                protein MetI.
FT                                /FTId=PRO_0000060099.
FT   TOPO_DOM      1     19       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     20     40       Helical. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00441}.
FT   TOPO_DOM     41     57       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     58     78       Helical. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00441}.
FT   TOPO_DOM     79     80       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     81    101       Helical. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00441}.
FT   TOPO_DOM    102    151       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    152    172       Helical. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00441}.
FT   TOPO_DOM    173    185       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    186    206       Helical. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00441}.
FT   TOPO_DOM    207    217       Cytoplasmic. {ECO:0000255}.
FT   DOMAIN       13    204       ABC transmembrane type-1.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00441}.
SQ   SEQUENCE   217 AA;  23242 MW;  3D8A304AFD4B0C35 CRC64;
     MSEPMMWLLV RGVWETLAMT FVSGFFGFVV GLPVGVLLYV TRPGQIIANA KLYRTVSAIV
     NIFRSIPFII LLVWMIPFTR VIVGTSIGLQ AAIVPLTVGA APFIARMVEN ALLEIPTGLI
     EASRAMGATP MQIVRKVLLP EALPGLVNAA TITLITLVGY SAMGGAVGAG GLGQIGYQYG
     YIGYNATVMN TVLVLLVILV YLIQFAGDRI VRAVTRK
//

If you have problems or comments...

PBIL Back to PBIL home page