(data stored in ACNUC7421 zone)

SWISSPROT: ECPE_ECO57

ID   ECPE_ECO57              Reviewed;         236 AA.
AC   Q8X6I6; Q7AHC4;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 2.
DT   05-JUL-2017, entry version 98.
DE   RecName: Full=Probable fimbrial chaperone EcpE;
DE   Flags: Precursor;
GN   Name=ecpE; Synonyms=yagV; OrderedLocusNames=Z0356, ECs0319;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [3]
RP   INDUCTION.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=22797761; DOI=10.1128/JB.00915-12;
RA   Martinez-Santos V.I., Medrano-Lopez A., Saldana Z., Giron J.A.,
RA   Puente J.L.;
RT   "Transcriptional regulation of the ecp operon by EcpR, IHF, and H-NS
RT   in attaching and effacing Escherichia coli.";
RL   J. Bacteriol. 194:5020-5033(2012).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli
CC       common pilus (ECP). ECP is found in both commensal and pathogenic
CC       strains and plays a dual role in early-stage biofilm development
CC       and host cell recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by
CC       IHF and EcpR. {ECO:0000269|PubMed:22797761}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG54614.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
CC       Sequence=BAB33742.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
DR   EMBL; AE005174; AAG54614.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB33742.1; ALT_INIT; Genomic_DNA.
DR   PIR; B85519; B85519.
DR   PIR; G90668; G90668.
DR   RefSeq; NP_308346.2; NC_002695.1.
DR   RefSeq; WP_001301550.1; NZ_MWVM01000043.1.
DR   SMR; Q8X6I6; -.
DR   STRING; 155864.Z0356; -.
DR   EnsemblBacteria; AAG54614; AAG54614; Z0356.
DR   EnsemblBacteria; BAB33742; BAB33742; BAB33742.
DR   GeneID; 914418; -.
DR   KEGG; ece:Z0356; -.
DR   KEGG; ecs:ECs0319; -.
DR   PATRIC; fig|386585.9.peg.413; -.
DR   eggNOG; ENOG4108UD7; Bacteria.
DR   eggNOG; ENOG4111HA8; LUCA.
DR   HOGENOM; HOG000269457; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8X6I6.
DR   SWISS-2DPAGE; Q8X6I6.
KW   Chaperone; Complete proteome; Fimbrium biogenesis; Signal.
FT   SIGNAL        1     27       {ECO:0000255}.
FT   CHAIN        28    236       Probable fimbrial chaperone EcpE.
FT                                /FTId=PRO_0000429539.
SQ   SEQUENCE   236 AA;  26650 MW;  6CA8076BF4A8F96E CRC64;
     MFRRRGVTLT KALLTAVCML AAPLTQAISV GNLTFSLPSE TDFVSKRVVN NNKSARIYRI
     AISAIDSPGS SELRTRPVDG ELLFAPRQLA LQAGESEYFK FYYHGPQDNR ERYYRVSFRE
     VPTRNLTKRS PTGGEVSTEP VVVMDTILVV RPRQVQFKWS FDQVTGTVSN TGNTWFKLLI
     KPGCDSTEEE GDAWYLRPED VVHQPELRQP GNHYLVYNDK FIKISDSCPA KPPSAD
//

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