(data stored in ACNUC7421 zone)

SWISSPROT: ECPC_ECO57

ID   ECPC_ECO57              Reviewed;         841 AA.
AC   Q8X6I4; Q7AHC2;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 86.
DE   RecName: Full=Probable outer membrane usher protein EcpC;
DE   Flags: Precursor;
GN   Name=ecpC; Synonyms=yagX; OrderedLocusNames=Z0358, ECs0321;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [3]
RP   INDUCTION.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=22797761; DOI=10.1128/JB.00915-12;
RA   Martinez-Santos V.I., Medrano-Lopez A., Saldana Z., Giron J.A.,
RA   Puente J.L.;
RT   "Transcriptional regulation of the ecp operon by EcpR, IHF, and H-NS
RT   in attaching and effacing Escherichia coli.";
RL   J. Bacteriol. 194:5020-5033(2012).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli
CC       common pilus (ECP). ECP is found in both commensal and pathogenic
CC       strains and plays a dual role in early-stage biofilm development
CC       and host cell recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by
CC       IHF and EcpR. {ECO:0000269|PubMed:22797761}.
CC   -!- SIMILARITY: Belongs to the EcpC/MatD family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54616.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33744.1; -; Genomic_DNA.
DR   PIR; A90669; A90669.
DR   PIR; D85519; D85519.
DR   RefSeq; NP_308348.1; NC_002695.1.
DR   RefSeq; WP_001131063.1; NZ_MWVM01000043.1.
DR   STRING; 155864.Z0358; -.
DR   EnsemblBacteria; AAG54616; AAG54616; Z0358.
DR   EnsemblBacteria; BAB33744; BAB33744; BAB33744.
DR   GeneID; 914420; -.
DR   KEGG; ece:Z0358; -.
DR   KEGG; ecs:ECs0321; -.
DR   PATRIC; fig|386585.9.peg.415; -.
DR   eggNOG; ENOG4108N3D; Bacteria.
DR   eggNOG; ENOG4110Z57; LUCA.
DR   HOGENOM; HOG000269481; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008969; CarboxyPept-like_regulatory.
DR   InterPro; IPR031917; Pilus_assem_C.
DR   InterPro; IPR032636; Pilus_assem_E-set-like_dom.
DR   Pfam; PF15976; CooC_C; 1.
DR   Pfam; PF16967; TcfC; 1.
DR   SUPFAM; SSF49464; SSF49464; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8X6I4.
DR   SWISS-2DPAGE; Q8X6I4.
KW   Complete proteome; Fimbrium biogenesis; Signal; Transport.
FT   SIGNAL        1     29       {ECO:0000255}.
FT   CHAIN        30    841       Probable outer membrane usher protein
FT                                EcpC.
FT                                /FTId=PRO_0000429531.
SQ   SEQUENCE   841 AA;  91227 MW;  DCCB0ACA1CB821E5 CRC64;
     MPLRRFSPGL KAQFAFGMVF LFVQPDASAA DISAQQIGGV IIPQAFSQAL QDGMSVPLYI
     HLAGSQGRQD DQRIGSAFIW LDDGQLRIRK IQLEESEDNA SVSEQTRQQL MALANAPFNE
     ALTIPLTDNA QLDLSLRQLL LQLVVKREAL GTVLRSRSED IGQSSVNTLS SNLSYNFGIY
     NNQLRNGGSN TSSYLSLNNV TALREHHVVL DGSLYGIGSG QQDSELYKAM YERDFAGHRF
     AGGTLDTWNL QSLGPMTAIS AGKIYGLSWG NQASSTIFDS SQSATPVIAF LPAAGEVHLT
     RDGRLLSVQN FTMGNHEVDT RGLPYGIYDV EVEVIVNGRV ISKRTQRVNK LFSRGRGVGA
     PLAWQVWGGS FHMDRWSENG KKTRPAKESW LAGASTSGSL STLSWAATGY GYDNQAVGET
     RLTLPLGGAI NVNLQNMLAS DSSWSSIGSI SATLPGGFSS LWVNQEKTRI GNQLRRSDAD
     NRAIGGTLNL NSLWSKLGTF SISYNDDRRY NSHYYTADYY QNVYSGTFGS LGLRAGIQRY
     NNGDSNANTG KYIALDLSLP LGNWFSAGMT HQNGYTMANL SARKQFDEGT IRTVGANLSR
     AISGDTGDDK TLSGGAYAQF DARYASGTLN VNSAADGYVN TNLTANGSVG WQGKNIAASG
     RTDGNAGVIF NTGLEDDGQI SAKINGRIFP LNGKRNYLPL SPYGRYEVEL QNSKNSLDSY
     DIVSGRKSHL TLYPGNVAVI EPEVKQMVTV SGRIRAEDGT LLANARINNH IGRTRTDENG
     EFVMDVDKKY PTIDFRYSGN KTCEVALELN QARGAVWVGD VVCSGLSSWA AVTQTGEENE
     S
//

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