(data stored in ACNUC7421 zone)

SWISSPROT: ECPB_ECO57

ID   ECPB_ECO57              Reviewed;         222 AA.
AC   Q8X6I2; Q7AHC1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   08-MAY-2019, entry version 88.
DE   RecName: Full=Probable fimbrial chaperone EcpB;
DE   Flags: Precursor;
GN   Name=ecpB; Synonyms=matC; OrderedLocusNames=Z0359, ECs0322;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [3]
RP   INDUCTION.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=22797761; DOI=10.1128/JB.00915-12;
RA   Martinez-Santos V.I., Medrano-Lopez A., Saldana Z., Giron J.A.,
RA   Puente J.L.;
RT   "Transcriptional regulation of the ecp operon by EcpR, IHF, and H-NS
RT   in attaching and effacing Escherichia coli.";
RL   J. Bacteriol. 194:5020-5033(2012).
CC   -!- FUNCTION: Part of the ecpRABCDE operon, which encodes the E.coli
CC       common pilus (ECP). ECP is found in both commensal and pathogenic
CC       strains and plays a dual role in early-stage biofilm development
CC       and host cell recognition (By similarity). {ECO:0000250}.
CC   -!- INDUCTION: Negatively regulated by H-NS. Positively regulated by
CC       IHF and EcpR. {ECO:0000269|PubMed:22797761}.
CC   -!- SIMILARITY: Belongs to the EcpB/EcpE family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54617.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33745.1; -; Genomic_DNA.
DR   PIR; B90669; B90669.
DR   PIR; E85519; E85519.
DR   RefSeq; NP_308349.1; NC_002695.1.
DR   RefSeq; WP_000716386.1; NZ_SDVX01000001.1.
DR   SMR; Q8X6I2; -.
DR   STRING; 155864.EDL933_0323; -.
DR   PRIDE; Q8X6I2; -.
DR   EnsemblBacteria; AAG54617; AAG54617; Z0359.
DR   EnsemblBacteria; BAB33745; BAB33745; BAB33745.
DR   GeneID; 914421; -.
DR   KEGG; ece:Z0359; -.
DR   KEGG; ecs:ECs0322; -.
DR   PATRIC; fig|386585.9.peg.416; -.
DR   eggNOG; ENOG4108NN8; Bacteria.
DR   eggNOG; ENOG41119MM; LUCA.
DR   HOGENOM; HOG000269492; -.
DR   KO; K21965; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040695; EcpB_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF18649; EcpB_C; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8X6I2.
DR   SWISS-2DPAGE; Q8X6I2.
KW   Chaperone; Complete proteome; Fimbrium biogenesis; Reference proteome;
KW   Signal.
FT   SIGNAL        1     20       {ECO:0000255}.
FT   CHAIN        21    222       Probable fimbrial chaperone EcpB.
FT                                /FTId=PRO_0000369161.
SQ   SEQUENCE   222 AA;  24513 MW;  C856108D49022473 CRC64;
     MKKHLLLLAL LLSGISPAQA LDVGDISSFM NSDSSTLSKT IKNSTDSGRL INIRLERLSS
     PLDDGQVISM DKPDELLLTP ASLLLPAQAS EVIRFFYKGP ADEKERYYRI VWFDQALSDA
     QRDNANRSAV ATASARIGTI LVVAPRQANY HFQYANGTLT NTGNATLRIL AYGPCLKAAN
     GKECKENYYL MPGKSRRFTR VDTADNKGRV ALWQGDKFIP VK
//

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