(data stored in ACNUC7421 zone)

SWISSPROT: SBMA_ECO57

ID   SBMA_ECO57              Reviewed;         406 AA.
AC   P0AFY7; P24212; P71313; P75702;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   05-JUL-2017, entry version 72.
DE   RecName: Full=Peptide antibiotic transporter SbmA;
GN   Name=sbmA; OrderedLocusNames=Z0473, ECs0427;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Uptake of antimicrobial peptides. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peptide uptake permease (PUP)
CC       (TC 9.A.18) family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54723.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33850.1; -; Genomic_DNA.
DR   PIR; C90682; C90682.
DR   PIR; G85532; G85532.
DR   RefSeq; NP_308454.1; NC_002695.1.
DR   RefSeq; WP_001301663.1; NZ_MWVM01000022.1.
DR   ProteinModelPortal; P0AFY7; -.
DR   STRING; 155864.Z0473; -.
DR   EnsemblBacteria; AAG54723; AAG54723; Z0473.
DR   EnsemblBacteria; BAB33850; BAB33850; BAB33850.
DR   GeneID; 914529; -.
DR   KEGG; ece:Z0473; -.
DR   KEGG; ecs:ECs0427; -.
DR   PATRIC; fig|386585.9.peg.522; -.
DR   eggNOG; ENOG4108DQG; Bacteria.
DR   eggNOG; COG1133; LUCA.
DR   HOGENOM; HOG000100637; -.
DR   KO; K17938; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR011527; ABC1_TM_dom.
DR   InterPro; IPR009248; SbmA_BacA.
DR   Pfam; PF05992; SbmA_BacA; 1.
DR   SUPFAM; SSF90123; SSF90123; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0AFY7.
DR   SWISS-2DPAGE; P0AFY7.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Peptide transport; Protein transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    406       Peptide antibiotic transporter SbmA.
FT                                /FTId=PRO_0000097604.
FT   TOPO_DOM      1     11       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     12     32       Helical. {ECO:0000255}.
FT   TOPO_DOM     33     56       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     57     77       Helical. {ECO:0000255}.
FT   TOPO_DOM     78     87       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     88    108       Helical. {ECO:0000255}.
FT   TOPO_DOM    109    137       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    138    158       Helical. {ECO:0000255}.
FT   TOPO_DOM    159    205       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    206    226       Helical. {ECO:0000255}.
FT   TOPO_DOM    227    242       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    243    263       Helical. {ECO:0000255}.
FT   TOPO_DOM    264    331       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    332    352       Helical. {ECO:0000255}.
FT   TOPO_DOM    353    406       Cytoplasmic. {ECO:0000255}.
SQ   SEQUENCE   406 AA;  46459 MW;  684057C831F624CD CRC64;
     MFKSFFPKPG TFFLSAFVWA LIAVIFWQAG GGDWVARITG ASGQIPISAA RFWSLDFLIF
     YAYYIVCVGL FALFWFIYSP HRWQYWSILG TALIIFVTWF LVEVGVAVNA WYAPFYDLIQ
     TALSSPHKVT IEQFYREVGV FLGIALIAVV ISVLNNFFVS HYVFRWRTAM NEYYMANWQQ
     LRHIEGAAQR VQEDTMRFAS TLENMGVSFI NAIMTLIAFL PVLVTLSAHV PELPIIGHIP
     YGLVIAAIVW SLMGTGLLAV VGIKLPGLEF KNQRVEAAYR KELVYGEDDA TRATPPTVRE
     LFSAVRKNYF RLYFHYMYFN IARILYLQVD NVFGLFLLFP SIVAGTITLG LMTQITNVFG
     QVRGAFQYLI NSWTTLVELM SIYKRLRSFE HELDGDKIQE VTHTLS
//

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