(data stored in ACNUC7421 zone)

SWISSPROT: IRAP_ECO57

ID   IRAP_ECO57              Reviewed;          86 AA.
AC   P0AAP0; P21831; P77383;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   05-JUL-2017, entry version 65.
DE   RecName: Full=Anti-adapter protein IraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   Name=iraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   OrderedLocusNames=Z0478, ECs0432;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS
CC       especially during phosphate starvation, but also in stationary
CC       phase and during nitrogen starvation. Its effect on RpoS stability
CC       is due to its interaction with RssB, which probably blocks the
CC       interaction of RssB with RpoS, and the consequent delivery of the
CC       RssB-RpoS complex to the ClpXP protein degradation pathway.
CC       {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBUNIT: Interacts with RssB. {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SIMILARITY: Belongs to the IraP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
DR   EMBL; AE005174; AAG54728.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33855.1; -; Genomic_DNA.
DR   PIR; D85533; D85533.
DR   PIR; H90682; H90682.
DR   RefSeq; NP_308459.1; NC_002695.1.
DR   RefSeq; WP_000792970.1; NZ_MWVM01000009.1.
DR   ProteinModelPortal; P0AAP0; -.
DR   SMR; P0AAP0; -.
DR   STRING; 155864.Z0478; -.
DR   EnsemblBacteria; AAG54728; AAG54728; Z0478.
DR   EnsemblBacteria; BAB33855; BAB33855; BAB33855.
DR   GeneID; 914534; -.
DR   KEGG; ece:Z0478; -.
DR   KEGG; ecs:ECs0432; -.
DR   PATRIC; fig|386585.9.peg.528; -.
DR   eggNOG; ENOG4105RZQ; Bacteria.
DR   eggNOG; ENOG4111YMR; LUCA.
DR   HOGENOM; HOG000059299; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01198; Anti_adapt_IraP; 1.
DR   InterPro; IPR019732; SigmaS_Anti-adapt_IraP.
DR   Pfam; PF10796; Anti-adapt_IraP; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0AAP0.
DR   SWISS-2DPAGE; P0AAP0.
KW   Coiled coil; Complete proteome; Cytoplasm; Stress response.
FT   CHAIN         1     86       Anti-adapter protein IraP.
FT                                /FTId=PRO_0000168586.
FT   COILED        1     36       {ECO:0000255|HAMAP-Rule:MF_01198}.
SQ   SEQUENCE   86 AA;  9937 MW;  1C2EE018BFB16BEE CRC64;
     MKNLIAELLF KLAQKEEESK ELCAQVEALE IIVTAMLRNM AQNDQQRLID QVEGALYEVK
     PDASIPDDDT ELLRDYVKKL LKHPRQ
//

If you have problems or comments...

PBIL Back to PBIL home page