(data stored in ACNUC7421 zone)

SWISSPROT: Q8XEB6_ECO57

ID   Q8XEB6_ECO57            Unreviewed;       494 AA.
AC   Q8XEB6; Q7AH29;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   30-AUG-2017, entry version 108.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:AAG54729.1};
GN   Name=phoA {ECO:0000313|EMBL:AAG54729.1};
GN   OrderedLocusNames=ECs0433 {ECO:0000313|EMBL:BAB33856.1}, Z0479
GN   {ECO:0000313|EMBL:AAG54729.1};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|Proteomes:UP000002519};
RN   [1] {ECO:0000313|EMBL:BAB33856.1, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC   {ECO:0000313|Proteomes:UP000000558}, and Sakai
RC   {ECO:0000313|EMBL:BAB33856.1};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2] {ECO:0000313|EMBL:AAG54729.1, ECO:0000313|Proteomes:UP000002519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EDL933 {ECO:0000313|EMBL:AAG54729.1}, and O157:H7 / EDL933 /
RC   ATCC 700927 / EHEC {ECO:0000313|Proteomes:UP000002519};
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G.III., Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
CC   -!- SIMILARITY: Belongs to the alkaline phosphatase family.
CC       {ECO:0000256|RuleBase:RU003946}.
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DR   EMBL; AE005174; AAG54729.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33856.1; -; Genomic_DNA.
DR   PIR; A99683; A99683.
DR   PIR; E85533; E85533.
DR   RefSeq; NP_308460.2; NC_002695.1.
DR   ProteinModelPortal; Q8XEB6; -.
DR   SMR; Q8XEB6; -.
DR   STRING; 155864.Z0479; -.
DR   PRIDE; Q8XEB6; -.
DR   EnsemblBacteria; AAG54729; AAG54729; Z0479.
DR   EnsemblBacteria; BAB33856; BAB33856; BAB33856.
DR   GeneID; 914535; -.
DR   KEGG; ece:Z0479; -.
DR   KEGG; ecs:ECs0433; -.
DR   PATRIC; fig|386585.9.peg.529; -.
DR   eggNOG; ENOG4105G6Z; Bacteria.
DR   eggNOG; COG1785; LUCA.
DR   HOGENOM; HOG000099117; -.
DR   KO; K01077; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   CDD; cd16012; ALP; 1.
DR   Gene3D; 3.40.720.10; -; 1.
DR   InterPro; IPR017849; Alkaline_Pase-like_a/b/a.
DR   InterPro; IPR001952; Alkaline_phosphatase.
DR   InterPro; IPR018299; Alkaline_phosphatase_AS.
DR   InterPro; IPR017850; Alkaline_phosphatase_core.
DR   PANTHER; PTHR11596; PTHR11596; 1.
DR   Pfam; PF00245; Alk_phosphatase; 1.
DR   PRINTS; PR00113; ALKPHPHTASE.
DR   SMART; SM00098; alkPPc; 1.
DR   SUPFAM; SSF53649; SSF53649; 1.
DR   PROSITE; PS00123; ALKALINE_PHOSPHATASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XEB6.
DR   SWISS-2DPAGE; Q8XEB6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558,
KW   ECO:0000313|Proteomes:UP000002519}.
SQ   SEQUENCE   494 AA;  52124 MW;  17B8CA6D33CA4EA8 CRC64;
     MSRPRLIVAL FLFFNVFVHG ENKVKQSTIA LALLPLLFTP VTKARTPEMP VLENRAAQGD
     ITAPGGARRL TADQTAALRD SLSDKPAKNI ILLIGDGMGD SEITAARNYA EGAGGFFKGI
     DALPLTGQYT HYALNKKTGK PDYVTDSAAS ATAWSTGVKT YNGALGVDIH EKDHPTILEM
     AKAAGLATGN VSTAELQDAT PAALVAHVTS RKCYGPSATS EKCPGNALEK GGKGSITEQL
     LNARADVTLG GGAKTFAETA TAGEWQGKTL REQAQARGYQ LVSDAASLNS VTEANQQKPL
     LGLFADGNMP VRWLGPKATY HGNIDKPAVT CTPNPQRNDS VPTLAQMTDK AIELLSKNEK
     GFFLQVEGAS IDKQDHAANP CGQIGETVDL DEAVQRALEF AKKDGNTLVI VTADHAHASQ
     IVAPDTKAPG LTQALNTKDG AVMVMSYGNS EEDSQEHTGS QLRIAAYGPH AANVVGLTDQ
     TDLFYTMKAA LGLK
//

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