(data stored in ACNUC7421 zone)

SWISSPROT: BRNQ_ECO57

ID   BRNQ_ECO57              Reviewed;         439 AA.
AC   P0ADA0; P37011; P77112; P77492;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   05-JUL-2017, entry version 78.
DE   RecName: Full=Branched-chain amino acid transport system 2 carrier protein;
DE   AltName: Full=LIV-II;
GN   Name=brnQ; OrderedLocusNames=Z0499, ECs0451;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Component of the LIV-II transport system for branched-
CC       chain amino acids. This LIV-II transport system may be H(+)-
CC       coupled (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC       family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54747.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33874.1; -; Genomic_DNA.
DR   PIR; C90685; C90685.
DR   PIR; G85535; G85535.
DR   RefSeq; NP_308478.1; NC_002695.1.
DR   RefSeq; WP_000149639.1; NZ_MWVM01000009.1.
DR   ProteinModelPortal; P0ADA0; -.
DR   STRING; 155864.Z0499; -.
DR   EnsemblBacteria; AAG54747; AAG54747; Z0499.
DR   EnsemblBacteria; BAB33874; BAB33874; BAB33874.
DR   GeneID; 914553; -.
DR   KEGG; ece:Z0499; -.
DR   KEGG; ecs:ECs0451; -.
DR   PATRIC; fig|386585.9.peg.551; -.
DR   eggNOG; ENOG4105CWM; Bacteria.
DR   eggNOG; COG1114; LUCA.
DR   HOGENOM; HOG000270688; -.
DR   KO; K03311; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR   PANTHER; PTHR30588; PTHR30588; 1.
DR   Pfam; PF05525; Branch_AA_trans; 1.
DR   TIGRFAMs; TIGR00796; livcs; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0ADA0.
DR   SWISS-2DPAGE; P0ADA0.
KW   Amino-acid transport; Cell inner membrane; Cell membrane;
KW   Complete proteome; Membrane; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    439       Branched-chain amino acid transport
FT                                system 2 carrier protein.
FT                                /FTId=PRO_0000099766.
FT   TOPO_DOM      1      9       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     10     30       Helical. {ECO:0000255}.
FT   TOPO_DOM     31     45       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     46     66       Helical. {ECO:0000255}.
FT   TOPO_DOM     67     79       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     80    100       Helical. {ECO:0000255}.
FT   TOPO_DOM    101    118       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    119    139       Helical. {ECO:0000255}.
FT   TOPO_DOM    140    149       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    150    170       Helical. {ECO:0000255}.
FT   TOPO_DOM    171    189       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    190    210       Helical. {ECO:0000255}.
FT   TOPO_DOM    211    226       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    227    247       Helical. {ECO:0000255}.
FT   TOPO_DOM    248    277       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    278    298       Helical. {ECO:0000255}.
FT   TOPO_DOM    299    316       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    317    337       Helical. {ECO:0000255}.
FT   TOPO_DOM    338    338       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    339    359       Helical. {ECO:0000255}.
FT   TOPO_DOM    360    369       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    370    390       Helical. {ECO:0000255}.
FT   TOPO_DOM    391    404       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    405    425       Helical. {ECO:0000255}.
FT   TOPO_DOM    426    439       Cytoplasmic. {ECO:0000255}.
SQ   SEQUENCE   439 AA;  46209 MW;  B30C3B5755738E0E CRC64;
     MTHQLRSRDI IALGFMTFAL FVGAGNIIFP PMVGLQAGEH VWTAAFGFLI TAVGLPVLTV
     VALAKVGGGV DSLSTPIGKV AGVLLATVCY LAVGPLFATP RTATVSFEVG IAPLTGDSAL
     PLFIYSLVYF AIVILVSLYP GKLLDTVGNF LAPLKIIALV ILSVAAIVWP AGSISTATEA
     YQNAAFSNGF VNGYLTMDTL GAMVFGIVIV NAARSRGVTE ARLLTRYTVW AGLMAGVGLT
     LLYLALFRLG SDSASLVDQS ANGAAILHAY VQHTFGGGGS FLLAALIFIA CLVTAVGLTC
     ACAEFFAQYV PLSYRTLVFI LGGFSMVVSN LGLSQLIQIS VPVLTAIYPP CIALVVLSFT
     RSWWHNSSRV IAPPMFISLL FGILDGIKAS AFSDILPSWA QRLPLAEQGL AWLMPTVVMV
     VLAIIWDRAA GRQVTSSAH
//

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