(data stored in ACNUC7421 zone)

SWISSPROT: ACPH_ECO57

ID   ACPH_ECO57              Reviewed;         193 AA.
AC   Q8XE96; Q7AH16;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   08-MAY-2019, entry version 93.
DE   RecName: Full=Acyl carrier protein phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            Short=ACP phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            EC=3.1.4.14 {ECO:0000255|HAMAP-Rule:MF_01950};
GN   Name=acpH {ECO:0000255|HAMAP-Rule:MF_01950};
GN   OrderedLocusNames=Z0503, ECs0455;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Converts holo-ACP to apo-ACP by hydrolytic cleavage of
CC       the phosphopantetheine prosthetic group from ACP.
CC       {ECO:0000255|HAMAP-Rule:MF_01950}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + holo-[ACP] = apo-[ACP] + D-pantetheine 4'-phosphate
CC         + H(+); Xref=Rhea:RHEA:20537, Rhea:RHEA-COMP:9685, Rhea:RHEA-
CC         COMP:9690, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29999, ChEBI:CHEBI:61723, ChEBI:CHEBI:64479;
CC         EC=3.1.4.14; Evidence={ECO:0000255|HAMAP-Rule:MF_01950};
CC   -!- SIMILARITY: Belongs to the AcpH family. {ECO:0000255|HAMAP-
CC       Rule:MF_01950}.
DR   EMBL; AE005174; AAG54751.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33878.1; -; Genomic_DNA.
DR   PIR; C85536; C85536.
DR   PIR; G90685; G90685.
DR   RefSeq; NP_308482.1; NC_002695.1.
DR   RefSeq; WP_001009882.1; NZ_SDVX01000001.1.
DR   STRING; 155864.EDL933_0469; -.
DR   EnsemblBacteria; AAG54751; AAG54751; Z0503.
DR   EnsemblBacteria; BAB33878; BAB33878; BAB33878.
DR   GeneID; 914557; -.
DR   KEGG; ece:Z0503; -.
DR   KEGG; ecs:ECs0455; -.
DR   PATRIC; fig|386585.9.peg.555; -.
DR   eggNOG; ENOG4108ZYK; Bacteria.
DR   eggNOG; COG3124; LUCA.
DR   HOGENOM; HOG000275880; -.
DR   KO; K08682; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0008770; F:[acyl-carrier-protein] phosphodiesterase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01950; AcpH; 1.
DR   InterPro; IPR007431; ACP_PD.
DR   InterPro; IPR023491; ACP_phosphodiesterase_gpbac.
DR   PANTHER; PTHR38764; PTHR38764; 1.
DR   Pfam; PF04336; ACP_PD; 1.
DR   PIRSF; PIRSF011489; DUF479; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XE96.
DR   SWISS-2DPAGE; Q8XE96.
KW   Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism;
KW   Hydrolase; Lipid biosynthesis; Lipid metabolism; Reference proteome.
FT   CHAIN         1    193       Acyl carrier protein phosphodiesterase.
FT                                /FTId=PRO_0000226266.
SQ   SEQUENCE   193 AA;  22917 MW;  F8E6F0CE01D6C395 CRC64;
     MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV LTDNLPEVRE
     AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM TILPDSPPRF
     INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLDAHY AALETRFWQF
     YPRMMAQASR KAL
//

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