(data stored in ACNUC7421 zone)

SWISSPROT: EX7S_ECO57

ID   EX7S_ECO57              Reviewed;          80 AA.
AC   P0A8H1; P22938;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=Exodeoxyribonuclease 7 small subunit;
DE            EC=3.1.11.6;
DE   AltName: Full=Exodeoxyribonuclease VII small subunit;
DE            Short=Exonuclease VII small subunit;
GN   Name=xseB; OrderedLocusNames=Z0525, ECs0476;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Bidirectionally degrades single-stranded DNA into large
CC       acid-insoluble oligonucleotides, which are then degraded further
CC       into small acid-soluble oligonucleotides. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to
CC         5'-direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC   -!- SUBUNIT: Heterooligomer composed of large and small subunits.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the XseB family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54772.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33899.1; -; Genomic_DNA.
DR   PIR; D90688; D90688.
DR   PIR; H85538; H85538.
DR   RefSeq; NP_308503.1; NC_002695.1.
DR   RefSeq; WP_001124935.1; NZ_SDVX01000001.1.
DR   SMR; P0A8H1; -.
DR   STRING; 155864.EDL933_0491; -.
DR   EnsemblBacteria; AAG54772; AAG54772; Z0525.
DR   EnsemblBacteria; BAB33899; BAB33899; BAB33899.
DR   GeneID; 914578; -.
DR   KEGG; ece:Z0525; -.
DR   KEGG; ecs:ECs0476; -.
DR   PATRIC; fig|386585.9.peg.576; -.
DR   eggNOG; ENOG41067QG; Bacteria.
DR   eggNOG; COG1722; LUCA.
DR   HOGENOM; HOG000228798; -.
DR   KO; K03602; -.
DR   BioCyc; ECOO157:XSEB-MONOMER; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR   GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.287.1040; -; 1.
DR   HAMAP; MF_00337; Exonuc_7_S; 1.
DR   InterPro; IPR003761; Exonuc_VII_S.
DR   InterPro; IPR037004; Exonuc_VII_ssu_sf.
DR   PANTHER; PTHR34137; PTHR34137; 1.
DR   Pfam; PF02609; Exonuc_VII_S; 1.
DR   PIRSF; PIRSF006488; Exonuc_VII_S; 1.
DR   ProDom; PD028235; Exonuc_VII_S; 1.
DR   TIGRFAMs; TIGR01280; xseB; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0A8H1.
DR   SWISS-2DPAGE; P0A8H1.
KW   Complete proteome; Cytoplasm; Exonuclease; Hydrolase; Nuclease;
KW   Reference proteome.
FT   INIT_MET      1      1       Removed. {ECO:0000250}.
FT   CHAIN         2     80       Exodeoxyribonuclease 7 small subunit.
FT                                /FTId=PRO_0000206946.
SQ   SEQUENCE   80 AA;  8952 MW;  8B10380D442CADF4 CRC64;
     MPKKNEAPAS FEKALSELEQ IVTRLESGDL PLEEALNEFE RGVQLARQGQ AKLQQAEQRV
     QILLSDNEDA SLTPFTPDNE
//

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