(data stored in ACNUC7421 zone)

SWISSPROT: CYOD_ECO57

ID   CYOD_ECO57              Reviewed;         109 AA.
AC   P0ABJ7; P18403; P77116;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   05-JUL-2017, entry version 73.
DE   RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE   AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE            Short=Cytochrome o subunit 4;
DE   AltName: Full=Oxidase bo(3) subunit 4;
DE   AltName: Full=Ubiquinol oxidase chain D;
DE   AltName: Full=Ubiquinol oxidase polypeptide IV;
DE   AltName: Full=Ubiquinol oxidase subunit 4;
GN   Name=cyoD; OrderedLocusNames=Z0532, ECs0483;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the
CC       component of the aerobic respiratory chain of E.coli that
CC       predominates when cells are grown at high aeration. Has proton
CC       pump activity across the membrane in addition to electron
CC       transfer, pumping 2 protons/electron (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains
CC       and two D chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit
CC       4 family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54779.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33906.1; -; Genomic_DNA.
DR   PIR; C90689; C90689.
DR   PIR; G85539; G85539.
DR   RefSeq; NP_308510.1; NC_002695.1.
DR   RefSeq; WP_000019869.1; NZ_MWVM01000009.1.
DR   ProteinModelPortal; P0ABJ7; -.
DR   STRING; 155864.Z0532; -.
DR   EnsemblBacteria; AAG54779; AAG54779; Z0532.
DR   EnsemblBacteria; BAB33906; BAB33906; BAB33906.
DR   GeneID; 914585; -.
DR   KEGG; ece:Z0532; -.
DR   KEGG; ecs:ECs0483; -.
DR   PATRIC; fig|386585.9.peg.584; -.
DR   eggNOG; ENOG41090KH; Bacteria.
DR   eggNOG; COG3125; LUCA.
DR   HOGENOM; HOG000087516; -.
DR   KO; K02300; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008827; F:cytochrome o ubiquinol oxidase activity; IEA:InterPro.
DR   GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR   InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR   InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR   Pfam; PF03626; COX4_pro; 1.
DR   TIGRFAMs; TIGR02847; CyoD; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0ABJ7.
DR   SWISS-2DPAGE; P0ABJ7.
KW   Cell inner membrane; Cell membrane; Complete proteome;
KW   Electron transport; Membrane; Oxidoreductase; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    109       Cytochrome bo(3) ubiquinol oxidase
FT                                subunit 4.
FT                                /FTId=PRO_0000183911.
FT   TOPO_DOM      1     17       Cytoplasmic. {ECO:0000305}.
FT   TRANSMEM     18     36       Helical. {ECO:0000305}.
FT   TOPO_DOM     37     45       Periplasmic. {ECO:0000305}.
FT   TRANSMEM     46     64       Helical. {ECO:0000305}.
FT   TOPO_DOM     65     80       Cytoplasmic. {ECO:0000305}.
FT   TRANSMEM     81     99       Helical. {ECO:0000305}.
FT   TOPO_DOM    100    109       Periplasmic. {ECO:0000305}.
SQ   SEQUENCE   109 AA;  12029 MW;  E2DBE23C893724BA CRC64;
     MSHSTDHSGA SHGSVKTYMT GFILSIILTV IPFWMVMTGA ASPAVILGTI LAMAVVQVLV
     HLVCFLHMNT KSDEGWNMTA FVFTVLIIAI LVVGSIWIMW NLNYNMMMH
//

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