(data stored in ACNUC7421 zone)

SWISSPROT: DECR_ECO57

ID   DECR_ECO57              Reviewed;         152 AA.
AC   P0ACJ7; P54986; P71209; P77575;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   05-JUL-2017, entry version 84.
DE   RecName: Full=DNA-binding transcriptional activator DecR;
GN   Name=decR; OrderedLocusNames=Z0555, ECs0501;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Plays a role in L-cysteine detoxification. Binds to the
CC       dlsT(yhaO)-yhaM operon promoter in the presence but not absence of
CC       L-cysteine; activates transcription from the dlsT(yhaO)-yhaM
CC       operon. {ECO:0000250|UniProtKB:P0ACJ5}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB33924.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
DR   EMBL; AE005174; AAG54797.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33924.1; ALT_INIT; Genomic_DNA.
DR   PIR; A85542; A85542.
DR   RefSeq; NP_308528.2; NC_002695.1.
DR   RefSeq; WP_000884589.1; NZ_MWVM01000009.1.
DR   ProteinModelPortal; P0ACJ7; -.
DR   SMR; P0ACJ7; -.
DR   STRING; 155864.Z0555; -.
DR   EnsemblBacteria; AAG54797; AAG54797; Z0555.
DR   EnsemblBacteria; BAB33924; BAB33924; BAB33924.
DR   GeneID; 914603; -.
DR   KEGG; ece:Z0555; -.
DR   KEGG; ecs:ECs0501; -.
DR   PATRIC; fig|386585.9.peg.605; -.
DR   eggNOG; ENOG4108XM1; Bacteria.
DR   eggNOG; COG1522; LUCA.
DR   HOGENOM; HOG000115328; -.
DR   KO; K05800; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-typ.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   Pfam; PF13404; HTH_AsnC-type; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS00519; HTH_ASNC_1; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0ACJ7.
DR   SWISS-2DPAGE; P0ACJ7.
KW   Activator; Complete proteome; DNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    152       DNA-binding transcriptional activator
FT                                DecR.
FT                                /FTId=PRO_0000111748.
FT   DOMAIN        2     63       HTH asnC-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00319}.
FT   DNA_BIND     21     40       H-T-H motif. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00319}.
SQ   SEQUENCE   152 AA;  17437 MW;  8409CEDC4CA3D012 CRC64;
     MLDKIDRKLL ALLQQDCTLS LQALAEAVNL TTTPCWKRLK RLEDDGILIG KVALLDPEKI
     GLGLTAFVLI KTQHHSSEWY CRFVTVVTEM PEVLGFWRMA GEYDYLMRVQ VADMKRYDEF
     YKRLVNSVPG LSDVTSSFAM EQIKYTTSLP IE
//

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