(data stored in ACNUC7421 zone)

SWISSPROT: ARCC_ECO57

ID   ARCC_ECO57              Reviewed;         297 AA.
AC   Q8XCV5;
DT   23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 88.
DE   RecName: Full=Carbamate kinase;
DE            EC=2.7.2.2;
GN   Name=arcC; OrderedLocusNames=Z0676, ECs0583;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- CATALYTIC ACTIVITY: ATP + NH(3) + CO(2) = ADP + carbamoyl
CC       phosphate.
CC   -!- PATHWAY: Metabolic intermediate metabolism; carbamoyl phosphate
CC       degradation; CO(2) and NH(3) from carbamoyl phosphate: step 1/1.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the carbamate kinase family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54878.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34006.1; -; Genomic_DNA.
DR   PIR; B85552; B85552.
DR   PIR; G90701; G90701.
DR   RefSeq; NP_308610.1; NC_002695.1.
DR   RefSeq; WP_000855395.1; NZ_MWVM01000032.1.
DR   ProteinModelPortal; Q8XCV5; -.
DR   SMR; Q8XCV5; -.
DR   STRING; 155864.Z0676; -.
DR   EnsemblBacteria; AAG54878; AAG54878; Z0676.
DR   EnsemblBacteria; BAB34006; BAB34006; BAB34006.
DR   GeneID; 916781; -.
DR   KEGG; ece:Z0676; -.
DR   KEGG; ecs:ECs0583; -.
DR   PATRIC; fig|386585.9.peg.690; -.
DR   eggNOG; ENOG4105C5B; Bacteria.
DR   eggNOG; COG0549; LUCA.
DR   HOGENOM; HOG000277403; -.
DR   KO; K00926; -.
DR   UniPathway; UPA00996; UER00366.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008804; F:carbamate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035975; P:carbamoyl phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd04235; AAK_CK; 1.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR003964; Carb_kinase.
DR   PANTHER; PTHR30409; PTHR30409; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF000723; Carbamate_kin; 1.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00746; arcC; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XCV5.
DR   SWISS-2DPAGE; Q8XCV5.
KW   Arginine metabolism; ATP-binding; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    297       Carbamate kinase.
FT                                /FTId=PRO_0000185121.
SQ   SEQUENCE   297 AA;  31731 MW;  6B9B2DD6DA78CF51 CRC64;
     MKTLVVALGG NALLQRGEAL TAENQYRNIA SAVPALARLA RSYRLAIVHG NGPQVGLLAL
     QNLAWKEVEP YPLDVLVAES QGMIGYMLAQ SLSAQPQMPP VTTVRTRIEV SPDDPAFLQP
     EKFIGPVYQP EEQEALEAAY GWQMKRDGKY LRRVVASPQP RKILDSEAIE LLLKEGHVVI
     CSGGGGVPVT DDGAGSEAVI DKDLAAALLA EQINADGLVI LTDADAVYEN WGMPQQRAIR
     HATPDELAPF AKADGSMGPK VTAVSGYVRS RGKPAWIGAL SRIEETLAGE AGTCISL
//

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