(data stored in ACNUC7421 zone)

SWISSPROT: HOKE_ECO57

ID   HOKE_ECO57              Reviewed;          50 AA.
AC   Q8XBW9; Q7AGS2;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 2.
DT   05-JUL-2017, entry version 79.
DE   RecName: Full=Protein HokE;
GN   Name=hokE; OrderedLocusNames=Z0722, ECs0621;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the hok/gef family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG54916.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB34044.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR   EMBL; AE005174; AAG54916.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB34044.1; ALT_INIT; Genomic_DNA.
DR   PIR; E90706; E90706.
DR   PIR; H85556; H85556.
DR   RefSeq; NP_308648.1; NC_002695.1.
DR   RefSeq; WP_000956465.1; NZ_MWVM01000011.1.
DR   STRING; 155864.Z0722; -.
DR   EnsemblBacteria; AAG54916; AAG54916; Z0722.
DR   EnsemblBacteria; BAB34044; BAB34044; BAB34044.
DR   GeneID; 916980; -.
DR   KEGG; ece:Z0722; -.
DR   KEGG; ecs:ECs0621; -.
DR   PATRIC; fig|386585.9.peg.729; -.
DR   eggNOG; ENOG4107635; Bacteria.
DR   eggNOG; ENOG410Z5SJ; LUCA.
DR   HOGENOM; HOG000041219; -.
DR   KO; K18922; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000021; Hok/gef_toxin.
DR   InterPro; IPR018084; Hok/gef_toxin_CS.
DR   Pfam; PF01848; HOK_GEF; 1.
DR   PRINTS; PR00281; HOKGEFTOXIC.
DR   ProDom; PD005979; Hok/gef_toxin; 1.
DR   PROSITE; PS00556; HOK_GEF; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XBW9.
DR   SWISS-2DPAGE; Q8XBW9.
KW   Complete proteome; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN         1     50       Protein HokE.
FT                                /FTId=PRO_0000199037.
FT   TRANSMEM      5     25       Helical. {ECO:0000255}.
SQ   SEQUENCE   50 AA;  5592 MW;  8AD9BA232CEF6835 CRC64;
     MLTKYALVAV IVLCLTVLGF TLLVGDSLCE FTVKERNIEF KAVLAYEPKK
//

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