(data stored in ACNUC7421 zone)

SWISSPROT: ENTS_ECO57

ID   ENTS_ECO57              Reviewed;         416 AA.
AC   Q8X534; Q7AGR5;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   05-JUL-2017, entry version 93.
DE   RecName: Full=Enterobactin exporter EntS {ECO:0000255|HAMAP-Rule:MF_01436};
GN   Name=entS {ECO:0000255|HAMAP-Rule:MF_01436};
GN   OrderedLocusNames=Z0733, ECs0630;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Exports the siderophore enterobactin out of the cell.
CC       {ECO:0000255|HAMAP-Rule:MF_01436}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01436}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01436}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. EntS
CC       (TC 2.A.1.38) family. {ECO:0000255|HAMAP-Rule:MF_01436}.
DR   EMBL; BA000007; BAB34053.1; -; Genomic_DNA.
DR   EMBL; AE005174; AAG54926.1; -; Genomic_DNA.
DR   PIR; B85558; B85558.
DR   PIR; F90707; F90707.
DR   RefSeq; NP_308657.1; NC_002695.1.
DR   RefSeq; WP_001041788.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; Q8X534; -.
DR   STRING; 155864.Z0733; -.
DR   EnsemblBacteria; AAG54926; AAG54926; Z0733.
DR   EnsemblBacteria; BAB34053; BAB34053; BAB34053.
DR   GeneID; 916989; -.
DR   KEGG; ece:Z0733; -.
DR   KEGG; ecs:ECs0630; -.
DR   PATRIC; fig|386585.9.peg.740; -.
DR   eggNOG; ENOG4105E8G; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000183770; -.
DR   KO; K08225; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042931; F:enterobactin transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   HAMAP; MF_01436; MFS_EntS; 1.
DR   InterPro; IPR023722; Enterobactin_exp_EntS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR010290; TM_effector.
DR   Pfam; PF05977; MFS_3; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8X534.
DR   SWISS-2DPAGE; Q8X534.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN         1    416       Enterobactin exporter EntS.
FT                                /FTId=PRO_0000227649.
FT   TOPO_DOM      1     21       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM     22     42       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM     43     55       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM     56     76       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM     77     95       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM     96    116       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    117    118       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    119    139       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    140    156       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    157    177       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    178    178       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    179    199       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    200    218       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    219    239       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    240    256       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    257    277       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    278    300       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    301    321       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    322    356       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    357    377       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    378    378       Periplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TRANSMEM    379    399       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
FT   TOPO_DOM    400    416       Cytoplasmic. {ECO:0000255|HAMAP-
FT                                Rule:MF_01436}.
SQ   SEQUENCE   416 AA;  43271 MW;  793CCF9AF986305A CRC64;
     MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL
     TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD
     GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG
     LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS
     AVRVLYPALA DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL
     AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING LWTAQNVTGD
     AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE LRRFRQTPPQ VTASDG
//

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