(data stored in ACNUC7421 zone)

SWISSPROT: DSBG_ECO57

ID   DSBG_ECO57              Reviewed;         248 AA.
AC   P58320;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   18-OCT-2001, sequence version 1.
DT   05-JUL-2017, entry version 93.
DE   RecName: Full=Thiol:disulfide interchange protein DsbG;
DE   Flags: Precursor;
GN   Name=dsbG; OrderedLocusNames=Z0748, ECs0643;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Involved in disulfide bond formation. Functions probably
CC       as a disulfide isomerase with a narrower substrate specificity
CC       than DsbC. DsbG is maintained in a reduced state by DsbD. In
CC       vitro, displays chaperone activity in both redox states (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the thioredoxin family. DsbC subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG54939.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=BAB34066.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR   EMBL; AE005174; AAG54939.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB34066.1; ALT_INIT; Genomic_DNA.
DR   PIR; C90709; C90709.
DR   PIR; G85559; G85559.
DR   RefSeq; NP_308670.3; NC_002695.1.
DR   RefSeq; WP_001301891.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; P58320; -.
DR   SMR; P58320; -.
DR   STRING; 155864.Z0748; -.
DR   PRIDE; P58320; -.
DR   EnsemblBacteria; AAG54939; AAG54939; Z0748.
DR   EnsemblBacteria; BAB34066; BAB34066; BAB34066.
DR   GeneID; 917002; -.
DR   KEGG; ece:Z0748; -.
DR   KEGG; ecs:ECs0643; -.
DR   PATRIC; fig|386585.9.peg.754; -.
DR   eggNOG; ENOG4108KHN; Bacteria.
DR   eggNOG; COG1651; LUCA.
DR   HOGENOM; HOG000117889; -.
DR   KO; K03805; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   CDD; cd03020; DsbA_DsbC_DsbG; 1.
DR   InterPro; IPR033954; DiS-bond_Isoase_DsbC/G.
DR   InterPro; IPR018950; DiS-bond_isomerase_DsbC/G_N.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   Pfam; PF13098; Thioredoxin_2; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   SUPFAM; SSF54423; SSF54423; 1.
PE   3: Inferred from homology;
DR   PRODOM; P58320.
DR   SWISS-2DPAGE; P58320.
KW   Chaperone; Complete proteome; Disulfide bond; Periplasm;
KW   Redox-active center; Signal.
FT   SIGNAL        1     17       {ECO:0000250}.
FT   CHAIN        18    248       Thiol:disulfide interchange protein DsbG.
FT                                /FTId=PRO_0000034279.
FT   DISULFID    126    129       Redox-active. {ECO:0000250}.
SQ   SEQUENCE   248 AA;  27496 MW;  C7C42EB3DBF537DB CRC64;
     MLKKILLLAL LPAIAFAEEL PAPVKAIEKQ GITIIKTFDA PGGMKGYLGK YQDMGVTIYL
     TPDGKHAISG YMYNEKGENL SNTLIEKEIY APAGREMWQR MEQSHWLLDG KKDAPVIVYV
     FADPFCPYCK QFWQQARPWV DSGKVQLRTL LVGVIKPESP ATAAAILASK DPAKTWQEYE
     ASGGKLKLNV PANVSTEQMK VLSDNEKLMD DLGANVTPAI YYMSKENTLQ QAVGLPDQKT
     LNIIMGNK
//

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