(data stored in ACNUC7421 zone)

SWISSPROT: CITG_ECO57

ID   CITG_ECO57              Reviewed;         292 AA.
AC   P58161;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   05-JUL-2017, entry version 88.
DE   RecName: Full=2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase;
DE            Short=2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase;
DE            EC=2.4.2.52;
GN   Name=citG; OrderedLocusNames=Z0757, ECs0652;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-
CC       dephosphocoenzyme-A, the precursor of the prosthetic group of the
CC       holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP
CC       and dephospho-CoA. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = 2'-(5-triphospho-
CC       alpha-D-ribosyl)-3'-dephospho-CoA + adenine.
CC   -!- SIMILARITY: Belongs to the CitG/MdcB family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54948.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34075.1; -; Genomic_DNA.
DR   PIR; D90710; D90710.
DR   PIR; H85560; H85560.
DR   RefSeq; NP_308679.1; NC_002695.1.
DR   RefSeq; WP_000062434.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; P58161; -.
DR   STRING; 155864.Z0757; -.
DR   EnsemblBacteria; AAG54948; AAG54948; Z0757.
DR   EnsemblBacteria; BAB34075; BAB34075; BAB34075.
DR   GeneID; 917011; -.
DR   KEGG; ece:Z0757; -.
DR   KEGG; ecs:ECs0652; -.
DR   PATRIC; fig|386585.9.peg.763; -.
DR   eggNOG; ENOG4108K6F; Bacteria.
DR   eggNOG; COG1767; LUCA.
DR   HOGENOM; HOG000258582; -.
DR   KO; K05966; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046917; F:triphosphoribosyl-dephospho-CoA synthase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR   HAMAP; MF_00397; CitG; 1.
DR   InterPro; IPR002736; CitG.
DR   InterPro; IPR017551; TriPribosyl-deP-CoA_syn_CitG.
DR   Pfam; PF01874; CitG; 1.
DR   TIGRFAMs; TIGR03125; citrate_citG; 1.
PE   3: Inferred from homology;
DR   PRODOM; P58161.
DR   SWISS-2DPAGE; P58161.
KW   ATP-binding; Complete proteome; Nucleotide-binding; Transferase.
FT   CHAIN         1    292       2-(5''-triphosphoribosyl)-3'-
FT                                dephosphocoenzyme-A synthase.
FT                                /FTId=PRO_0000214666.
SQ   SEQUENCE   292 AA;  31701 MW;  E8CD067CE1DFFD31 CRC64;
     MSMPATLTKT TKLATSLIDE YALLGWRAML TEVNLSPKPG LVDRINCGAH KDMALEDFHR
     SALAIQGWLP RFIEFGACSA EMAPEAVLHG LRPIGMACEG DMFRATAGVN THKGSIFSLG
     LLCAAIGRLL QLNQLLTPTT VCSTAASFCR GLTDRELRTN NSQLTAGQRL YQQLGLTGAR
     GEAEAGYPLV INHALPHYLT LLDQGLDPEL ALLDTLLLLM AINGDTNVAS RGGEGGLRWL
     QREAQTLLQK GGIRTPADLD YLRQFDRECI ERNLSPGGSA DLLILTWFLA QI
//

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