(data stored in ACNUC7421 zone)

SWISSPROT: DCUC_ECO57

ID   DCUC_ECO57              Reviewed;         461 AA.
AC   P0ABP4; Q47134; Q9ZBC9; Q9ZBD0;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   05-JUL-2017, entry version 73.
DE   RecName: Full=Anaerobic C4-dicarboxylate transporter DcuC;
GN   Name=dcuC; OrderedLocusNames=Z0766, ECs0660;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Responsible for the transport of C4-dicarboxylates
CC       during anaerobic growth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DcuC/DcuD transporter (TC 2.A.61)
CC       family. {ECO:0000305}.
DR   EMBL; AE005174; AAG54956.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34083.1; -; Genomic_DNA.
DR   PIR; D90711; D90711.
DR   PIR; H85561; H85561.
DR   RefSeq; NP_308687.1; NC_002695.1.
DR   RefSeq; WP_000955063.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; P0ABP4; -.
DR   STRING; 155864.Z0766; -.
DR   EnsemblBacteria; AAG54956; AAG54956; Z0766.
DR   EnsemblBacteria; BAB34083; BAB34083; BAB34083.
DR   GeneID; 917020; -.
DR   KEGG; ece:Z0766; -.
DR   KEGG; ecs:ECs0660; -.
DR   PATRIC; fig|386585.9.peg.771; -.
DR   eggNOG; ENOG4105CEE; Bacteria.
DR   eggNOG; COG3069; LUCA.
DR   HOGENOM; HOG000274996; -.
DR   KO; K03326; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004669; C4_dicarb_anaerob_car.
DR   InterPro; IPR018385; C4_dicarb_anaerob_car-like.
DR   PANTHER; PTHR42002:SF3; PTHR42002:SF3; 1.
DR   Pfam; PF03606; DcuC; 1.
DR   TIGRFAMs; TIGR00771; DcuC; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0ABP4.
DR   SWISS-2DPAGE; P0ABP4.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN         1    461       Anaerobic C4-dicarboxylate transporter
FT                                DcuC.
FT                                /FTId=PRO_0000201628.
FT   TRANSMEM      2     22       Helical. {ECO:0000255}.
FT   TRANSMEM     26     46       Helical. {ECO:0000255}.
FT   TRANSMEM     79     99       Helical. {ECO:0000255}.
FT   TRANSMEM    116    136       Helical. {ECO:0000255}.
FT   TRANSMEM    137    157       Helical. {ECO:0000255}.
FT   TRANSMEM    164    184       Helical. {ECO:0000255}.
FT   TRANSMEM    199    219       Helical. {ECO:0000255}.
FT   TRANSMEM    240    260       Helical. {ECO:0000255}.
FT   TRANSMEM    267    287       Helical. {ECO:0000255}.
FT   TRANSMEM    313    333       Helical. {ECO:0000255}.
FT   TRANSMEM    343    363       Helical. {ECO:0000255}.
FT   TRANSMEM    436    456       Helical. {ECO:0000255}.
SQ   SEQUENCE   461 AA;  48412 MW;  D4042FBFE9F562ED CRC64;
     MLTFIELLIG VVVIVGVARY IIKGYSATGV LFVGGLLLLI ISAIMGHKVL PSSQASTGYS
     ATDIVEYVKI LLMSRGGDLG MMIMMLCGFA AYMTHIGAND MVVKLASKPL QYINSPYLLM
     IAAYFVACLM SLAVSSATGL GVLLMATLFP VMVNVGISRG AAAAICASPA AIILAPTSGD
     VVLAAQASEM SLIDFAFKTT LPISIAAIIG MAIAHFFWQR YLDKKEHISH EMLDVSEITT
     TAPAFYAILP FTPIIGVLIF DGKWGPQLHI ITILVICMLI ASILEFLRSF NTQKVFSGLE
     VAYRGMADAF ANVVMLLVAA GVFAQGLSTI GFIQSLISIA TSFGSASIIL MLVLVILTML
     AAVTTGSGNA PFYAFVEMIP KLAHSSGINP AYLTIPMLQA SNLGRTLSPV SGVVVAVAGM
     AKISPFEVVK RTSVPVLVGL VIVIVATELM VPGTAAAVTG K
//

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