(data stored in ACNUC7421 zone)

SWISSPROT: CRCB_ECO57

ID   CRCB_ECO57              Reviewed;         127 AA.
AC   P63861; Q8XBR8;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   05-JUL-2017, entry version 81.
DE   RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   OrderedLocusNames=Z0770, ECs0663;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the
CC       cell, thus reducing its toxicity. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family.
CC       {ECO:0000255|HAMAP-Rule:MF_00454}.
DR   EMBL; AE005174; AAG54959.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34086.1; -; Genomic_DNA.
DR   PIR; C85562; C85562.
DR   PIR; G90711; G90711.
DR   RefSeq; NP_308690.1; NC_002695.1.
DR   RefSeq; WP_000939738.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; P63861; -.
DR   SMR; P63861; -.
DR   STRING; 155864.Z0770; -.
DR   EnsemblBacteria; AAG54959; AAG54959; Z0770.
DR   EnsemblBacteria; BAB34086; BAB34086; BAB34086.
DR   GeneID; 917023; -.
DR   KEGG; ece:Z0770; -.
DR   KEGG; ecs:ECs0663; -.
DR   PATRIC; fig|386585.9.peg.774; -.
DR   eggNOG; ENOG4107Z6W; Bacteria.
DR   eggNOG; COG0239; LUCA.
DR   HOGENOM; HOG000052572; -.
DR   KO; K06199; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
DR   PRODOM; P63861.
DR   SWISS-2DPAGE; P63861.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN         1    127       Putative fluoride ion transporter CrcB.
FT                                /FTId=PRO_0000110098.
FT   TRANSMEM      4     24       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM     35     55       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM     71     91       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM    103    123       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
SQ   SEQUENCE   127 AA;  13765 MW;  492499959425EFE7 CRC64;
     MLQLLLAVFI GGGTGSVARW LLSMRFNPLH QAIPLGTLAA NLIGAFIIGM GFAWFSRMTN
     IDPVWKVLIT TGFCGGLTTF STFSAEVVFL LQEGRFGWAL LNVFVNLLGS FAMTALAFWL
     FSASTAH
//

If you have problems or comments...

PBIL Back to PBIL home page