(data stored in ACNUC7421 zone)

SWISSPROT: Q8XBP2_ECO57

ID   Q8XBP2_ECO57            Unreviewed;       105 AA.
AC   Q8XBP2; Q7AGP5;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 2.
DT   08-MAY-2019, entry version 105.
DE   RecName: Full=Ribosomal silencing factor RsfS {ECO:0000256|HAMAP-Rule:MF_01477};
GN   Name=rsfS {ECO:0000256|HAMAP-Rule:MF_01477,
GN   ECO:0000313|EMBL:BAB34098.2};
GN   ORFNames=ECs_0675 {ECO:0000313|EMBL:BAB34098.2};
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334 {ECO:0000313|EMBL:BAB34098.2, ECO:0000313|Proteomes:UP000000558};
RN   [1] {ECO:0000313|EMBL:BAB34098.2, ECO:0000313|Proteomes:UP000000558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 /
RC   EHEC {ECO:0000313|Proteomes:UP000000558};
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Functions as a ribosomal silencing factor. Interacts
CC       with ribosomal protein L14 (rplN), blocking formation of
CC       intersubunit bridge B8. Prevents association of the 30S and 50S
CC       ribosomal subunits and the formation of functional ribosomes, thus
CC       repressing translation. {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SUBUNIT: Interacts with ribosomal protein L14 (rplN).
CC       {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01477}.
CC   -!- SIMILARITY: Belongs to the Iojap/RsfS family. {ECO:0000256|HAMAP-
CC       Rule:MF_01477}.
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DR   EMBL; BA000007; BAB34098.2; -; Genomic_DNA.
DR   RefSeq; NP_308702.2; NC_002695.1.
DR   RefSeq; WP_001161664.1; NZ_SDVX01000001.1.
DR   SMR; Q8XBP2; -.
DR   STRING; 155864.EDL933_0711; -.
DR   EnsemblBacteria; AAG54971; AAG54971; Z0783.
DR   EnsemblBacteria; BAB34098; BAB34098; BAB34098.
DR   GeneID; 917036; -.
DR   KEGG; ecs:ECs0675; -.
DR   PATRIC; fig|386585.9.peg.787; -.
DR   eggNOG; ENOG4105KEM; Bacteria.
DR   eggNOG; COG0799; LUCA.
DR   KO; K09710; -.
DR   BioCyc; ECOO157:YBEB-MONOMER; -.
DR   Proteomes; UP000000558; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042256; P:mature ribosome assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0090071; P:negative regulation of ribosome biogenesis; IEA:UniProtKB-UniRule.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01477; Iojap_RsfS; 1.
DR   InterPro; IPR004394; Iojap/RsfS/C7orf30.
DR   PANTHER; PTHR21043; PTHR21043; 1.
DR   TIGRFAMs; TIGR00090; rsfS_iojap_ybeB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8XBP2.
DR   SWISS-2DPAGE; Q8XBP2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000558};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01477};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000558};
KW   Repressor {ECO:0000256|HAMAP-Rule:MF_01477};
KW   Translation regulation {ECO:0000256|HAMAP-Rule:MF_01477}.
SQ   SEQUENCE   105 AA;  11582 MW;  7C1315607BD0B610 CRC64;
     MQGKALQDFV IDKIDDLKGQ DIIALDVQGK SSITDCMIIC TGTSSRHVMS IADHVVQESR
     AAGLLPLGVE GENSADWIVV DLGDVIVHVM QEESRRLYEL EKLWS
//

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