(data stored in ACNUC7421 zone)

SWISSPROT: GLTK_ECO57

ID   GLTK_ECO57              Reviewed;         224 AA.
AC   P0AER7; P41075;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   05-JUL-2017, entry version 74.
DE   RecName: Full=Glutamate/aspartate import permease protein GltK {ECO:0000250|UniProtKB:P0AER5};
GN   Name=gltK; OrderedLocusNames=Z0803, ECs0692;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Part of the ABC transporter complex GltIJKL involved in
CC       glutamate and aspartate uptake. Probably responsible for the
CC       translocation of the substrate across the membrane.
CC       {ECO:0000250|UniProtKB:P0AER5}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (GltL), two transmembrane proteins (GltJ and GltK) and a solute-
CC       binding protein (GltI). {ECO:0000250|UniProtKB:P0AER5}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0AER5}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport
CC       system permease family. HisMQ subfamily. {ECO:0000305}.
DR   EMBL; AE005174; AAG54987.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34115.1; -; Genomic_DNA.
DR   PIR; D90715; D90715.
DR   PIR; G85565; G85565.
DR   RefSeq; NP_308719.1; NC_002695.1.
DR   RefSeq; WP_000272824.1; NZ_MWVM01000011.1.
DR   ProteinModelPortal; P0AER7; -.
DR   SMR; P0AER7; -.
DR   STRING; 155864.Z0803; -.
DR   EnsemblBacteria; AAG54987; AAG54987; Z0803.
DR   EnsemblBacteria; BAB34115; BAB34115; BAB34115.
DR   GeneID; 917053; -.
DR   KEGG; ece:Z0803; -.
DR   KEGG; ecs:ECs0692; -.
DR   PATRIC; fig|386585.9.peg.806; -.
DR   eggNOG; ENOG4105DRP; Bacteria.
DR   eggNOG; COG0765; LUCA.
DR   HOGENOM; HOG000267552; -.
DR   KO; K10002; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   CDD; cd06261; TM_PBP2; 1.
DR   InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR   InterPro; IPR030205; GltK/AatM.
DR   InterPro; IPR000515; MetI-like.
DR   PANTHER; PTHR30614:SF28; PTHR30614:SF28; 1.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR01726; HEQRo_perm_3TM; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0AER7.
DR   SWISS-2DPAGE; P0AER7.
KW   Amino-acid transport; Cell inner membrane; Cell membrane;
KW   Complete proteome; Membrane; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    224       Glutamate/aspartate import permease
FT                                protein GltK.
FT                                /FTId=PRO_0000060038.
FT   TOPO_DOM      1     19       Periplasmic. {ECO:0000305}.
FT   TRANSMEM     20     40       Helical. {ECO:0000255}.
FT   TOPO_DOM     41     67       Cytoplasmic. {ECO:0000305}.
FT   TRANSMEM     68     88       Helical. {ECO:0000255}.
FT   TOPO_DOM     89     94       Periplasmic. {ECO:0000305}.
FT   TRANSMEM     95    112       Helical. {ECO:0000255}.
FT   TOPO_DOM    113    154       Cytoplasmic. {ECO:0000305}.
FT   TRANSMEM    155    175       Helical. {ECO:0000255}.
FT   TOPO_DOM    176    196       Periplasmic. {ECO:0000305}.
FT   TRANSMEM    197    217       Helical. {ECO:0000255}.
FT   TOPO_DOM    218    224       Cytoplasmic.
FT                                {ECO:0000250|UniProtKB:P0AER5}.
FT   DOMAIN       20    216       ABC transmembrane type-1.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00441}.
SQ   SEQUENCE   224 AA;  24915 MW;  01BCB38D387807B6 CRC64;
     MYEFDWSSIV PSLPYLLDGL VITLKITVTA VVIGILWGTM LAVMRLSSFA PVAWFAKAYV
     NVFRSIPLVM VLLWFYLIVP GFLQNVLGLS PKNDIRLISA MVAFSMFEAA YYSEIIRAGI
     QSISRGQSSA ALALGMTHWQ SMKLIILPQA FRAMVPLLLT QGIVLFQDTS LVYVLSLADF
     FRTASTIGER DGTQVEMILF AGFVYFVISL SASLLVSYLK RRTA
//

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