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ID TSN11_MOUSE Reviewed; 253 AA.
AC Q9D1D1;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 08-MAY-2019, entry version 110.
DE RecName: Full=Tetraspanin-11;
DE Short=Tspan-11;
GN Name=Tspan11;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Colon, Eye, and Skin;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000305}.
DR EMBL; AK003691; BAB22942.1; -; mRNA.
DR EMBL; AK028808; BAC26129.1; -; mRNA.
DR EMBL; AK053788; BAC35523.1; -; mRNA.
DR EMBL; AK090022; BAC41051.1; -; mRNA.
DR EMBL; BC057639; AAH57639.1; -; mRNA.
DR CCDS; CCDS20567.1; -.
DR RefSeq; NP_081019.1; NM_026743.3.
DR STRING; 10090.ENSMUSP00000032501; -.
DR PaxDb; Q9D1D1; -.
DR PRIDE; Q9D1D1; -.
DR Ensembl; ENSMUST00000032501; ENSMUSP00000032501; ENSMUSG00000030351.
DR GeneID; 68498; -.
DR KEGG; mmu:68498; -.
DR UCSC; uc009ecn.1; mouse.
DR CTD; 441631; -.
DR MGI; MGI:1915748; Tspan11.
DR eggNOG; KOG3882; Eukaryota.
DR eggNOG; ENOG4111IRY; LUCA.
DR GeneTree; ENSGT00940000161249; -.
DR HOGENOM; HOG000230651; -.
DR InParanoid; Q9D1D1; -.
DR KO; K17352; -.
DR OMA; RLQLHFY; -.
DR OrthoDB; 1051357at2759; -.
DR PhylomeDB; Q9D1D1; -.
DR TreeFam; TF352892; -.
DR PRO; PR:Q9D1D1; -.
DR Proteomes; UP000000589; Chromosome 6.
DR Bgee; ENSMUSG00000030351; Expressed in 110 organ(s), highest expression level in ascending aorta.
DR Genevisible; Q9D1D1; MM.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 1.10.1450.10; -; 1.
DR InterPro; IPR000301; Tetraspanin.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; SSF48652; 1.
PE 2: Evidence at transcript level;
DR PRODOM; Q9D1D1.
DR SWISS-2DPAGE; Q9D1D1.
KW Complete proteome; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1 253 Tetraspanin-11.
FT /FTId=PRO_0000311906.
FT TRANSMEM 19 39 Helical. {ECO:0000255}.
FT TRANSMEM 63 83 Helical. {ECO:0000255}.
FT TRANSMEM 93 113 Helical. {ECO:0000255}.
FT TRANSMEM 220 240 Helical. {ECO:0000255}.
FT CARBOHYD 127 127 N-linked (GlcNAc...) asparagine.
FT {ECO:0000255}.
SQ SEQUENCE 253 AA; 28072 MW; 8A820157A945C60A CRC64;
MAHCKTEQDD WLLAHLKYLL FIFNFFFWVG GAAVMAVGIW TLVEKSGYLS ILASSTFAAS
AYILIFVGGL VMTTGFLGFG AIIREQKSCL STYFCLLLVI FLVELVAGVL AHVYYQRLSD
ELKWHLNSTL TEHYGQPRAA EITASVDRLQ QDFKCCGSNS SADWQHSAYI LSQEALGRQV
PDSCCKTVVA RCGQRAHPSN IYKVEGGCMA KLEQFVADHL LLMGAVGIGV ACLQICGMVL
TCCLHRRLQQ QFY
//
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